8DKT

Crystal Structure of Septin1 - Septin2 heterocomplex from Drosophila melanogaster

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Septin-1	polymer	275	31558.3	1	UniProt (P42207) Pfam (PF00735)	Drosophila melanogaster (fruit fly)	DIFF6 protein homolog,Protein innocent bystander
2	B (B)	Septin-2	polymer	282	32377.0	1	UniProt (P54359) Pfam (PF00735)	Drosophila melanogaster (fruit fly)
3	C (A)	GUANOSINE-5'-DIPHOSPHATE	non-polymer		443.2	1	Chemie (GDP)
4	D (B)	GUANOSINE-5'-TRIPHOSPHATE	non-polymer		523.2	1	Chemie (GTP)
5	E (B)	MAGNESIUM ION	non-polymer		24.3	1	Chemie (MG)
6	F, G (A, B)	water	water		18.0	39	Chemie (HOH)

Sequence modifications

A: 33 - 306 (UniProt: P42207)

PDB	External Database	Details
Met 32	-	initiating methionine

B: 41 - 308 (UniProt: P54359)

PDB	External Database	Details
Met 27	-	initiating methionine
Gly 28	-	expression tag
Ser 29	-	expression tag
Ser 30	-	expression tag
His 31	-	expression tag
His 32	-	expression tag
His 33	-	expression tag
His 34	-	expression tag
His 35	-	expression tag
His 36	-	expression tag
Ser 37	-	expression tag
Gln 38	-	expression tag
Asp 39	-	expression tag
Pro 40	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	63935.3
Non-Polymers*	Number of molecules	3
	Total formula weight	990.7
All*	Total formula weight	64926.0

*Water molecules are not included.