8DKS

IRAK4 IN COMPLEX WITH COMPOUND #3

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Interleukin-1 receptor-associated kinase 4	polymer	460	51669.5	2	UniProt (Q9NWZ3) Pfam (PF07714)	Homo sapiens (human)	IRAK-4,Renal carcinoma antigen NY-REN-64
2	C, E (A, B)	(1S,2S,3R,4R)-3-({2-[3-(pyrrolidine-1-carbonyl)anilino]thieno[3,2-d]pyrimidin-4-yl}amino)bicyclo[2.2.1]hept-5-ene-2-carboxamide	non-polymer		474.6	2	Chemie (SO9)
3	D, F (A, B)	BETA-MERCAPTOETHANOL	non-polymer		78.1	2	Chemie (BME)
4	G, H (A, B)	water	water		18.0	55	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	103339.1
Non-Polymers*	Number of molecules	4
	Total formula weight	1105.4
All*	Total formula weight	104444.5

*Water molecules are not included.