8DKB

Crystal Structure of human YEATS4 in complex with Pfizer small molecule compound 3b

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	YEATS domain-containing protein 4	polymer	155	18230.9	8	UniProt (O95619) Pfam (PF03366)	Homo sapiens (human)	Glioma-amplified sequence 41,Gas41,NuMA-binding protein 1,NuBI-1,NuBI1
2	I, J, K, L, M... (A, B, C, D, E...)	N-ethyl-1-{(3S,4S)-1-[(1-hydroxycyclohexyl)methyl]-3-methylpiperidin-4-yl}-2-methyl-1H-benzimidazole-5-carboxamide	non-polymer		412.6	8	Chemie (SJI)
3	Q, R, S, T, U... (A, B, C, D, E...)	water	water		18.0	334	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F, G, H: 1 - 149 (UniProt: O95619)

PDB	External Database	Details
His 150	-	expression tag
His 151	-	expression tag
His 152	-	expression tag
His 153	-	expression tag
His 154	-	expression tag
His 155	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	145847.1
Non-Polymers*	Number of molecules	8
	Total formula weight	3300.5
All*	Total formula weight	149147.6

*Water molecules are not included.