8DKB
Crystal Structure of human YEATS4 in complex with Pfizer small molecule compound 3b
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D, E... | YEATS domain-containing protein 4 | polymer | 155 | 18230.9 | 8 | UniProt (O95619) Pfam (PF03366) In PDB | Homo sapiens (human) | Glioma-amplified sequence 41,Gas41,NuMA-binding protein 1,NuBI-1,NuBI1 |
2 | A, B, C, D, E... | N-ethyl-1-{(3S,4S)-1-[(1-hydroxycyclohexyl)methyl]-3-methylpiperidin-4-yl}-2-methyl-1H-benzimidazole-5-carboxamide | non-polymer | 412.6 | 8 | Chemie (SJI) | |||
3 | water | water | 18.0 | 334 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F, G, H: 1 - 149 (UniProt: O95619)
PDB | External Database | Details |
---|---|---|
His 150 | - | expression tag |
His 151 | - | expression tag |
His 152 | - | expression tag |
His 153 | - | expression tag |
His 154 | - | expression tag |
His 155 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 8 |
Total formula weight | 145847.1 | |
Non-Polymers* | Number of molecules | 8 |
Total formula weight | 3300.5 | |
All* | Total formula weight | 149147.6 |