8DKB

Crystal Structure of human YEATS4 in complex with Pfizer small molecule compound 3b

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0006355	biological_process	regulation of DNA-templated transcription
B	0006355	biological_process	regulation of DNA-templated transcription
C	0006355	biological_process	regulation of DNA-templated transcription
D	0006355	biological_process	regulation of DNA-templated transcription
E	0006355	biological_process	regulation of DNA-templated transcription
F	0006355	biological_process	regulation of DNA-templated transcription
G	0006355	biological_process	regulation of DNA-templated transcription
H	0006355	biological_process	regulation of DNA-templated transcription

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	32
Details	Region: {"description":"Diacetylated histone H3 binding","evidences":[{"source":"PubMed","id":"29900004","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"30071723","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5VNB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5XTZ","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	8
Details	Site: {"description":"Interacts with diacetylated histone H3","evidences":[{"source":"PubMed","id":"29900004","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"30071723","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5VNB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5XTZ","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	16
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"source":"PubMed","id":"28112733","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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