8DJM
HMGCR-UBIAD1 Complex State 1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | polymer | 364 | 41215.9 | 1 | UniProt (P00347) Pfam (PF12349) | Cricetulus griseus (Chinese hamster) | HMG-CoA reductase |
| 2 | B (B) | UbiA prenyltransferase domain-containing protein 1 | polymer | 301 | 32780.5 | 1 | UniProt (G3IEF0) Pfam (PF01040) | Cricetulus griseus (Chinese hamster) | |
| 3 | C (C) | Soluble cytochrome b562 | polymer | 120 | 13470.2 | 1 | UniProt (P0ABE7) Pfam (PF07361) | Escherichia coli | Cytochrome b-562 |
| 4 | D (L) | Fab 15B2 Light Chain | polymer | 214 | 23373.8 | 1 | Mus musculus | ||
| 5 | E (H) | Fab 15B2 Heavy Chain | polymer | 232 | 25175.2 | 1 | Mus musculus | ||
| 6 | F, G, H, I, K... (A, B) | CHOLESTEROL HEMISUCCINATE | non-polymer | 486.7 | 6 | Chemie (Y01) | |||
| 7 | J, L (A, B) | Digitonin | non-polymer | 1229.3 | 2 | Chemie (AJP) |
Sequence modifications
A: 2 - 356 (UniProt: P00347)
B: 41 - 338 (UniProt: G3IEF0)
C: 269 - 371 (UniProt: P0ABE7)
| PDB | External Database | Details |
|---|---|---|
| Met -7 | - | expression tag |
| Asp -6 | - | expression tag |
| Tyr -5 | - | expression tag |
| Lys -4 | - | expression tag |
| Asp -3 | - | expression tag |
| Asp -2 | - | expression tag |
| Asp -1 | - | expression tag |
| Asp 0 | - | expression tag |
| Lys 1 | - | expression tag |
| Arg 89 | Lys 89 | conflict |
| Arg 248 | Lys 248 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Met 38 | - | initiating methionine |
| Ala 39 | - | expression tag |
| Ser 40 | - | expression tag |
| Ser 102 | Asn 102 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Ala 264 | - | expression tag |
| Arg 265 | - | expression tag |
| Arg 266 | - | expression tag |
| Leu 267 | - | expression tag |
| Ala 268 | - | expression tag |
| Trp 273 | Met 29 | conflict |
| Ile 368 | His 124 | conflict |
| Leu 372 | - | expression tag |
| Glu 373 | - | expression tag |
| Arg 374 | - | expression tag |
| Ala 375 | - | expression tag |
| Arg 376 | - | expression tag |
| Ser 377 | - | expression tag |
| Thr 378 | - | expression tag |
| Leu 379 | - | expression tag |
| Gln 380 | - | expression tag |
| Lys 381 | - | expression tag |
| Glu 382 | - | expression tag |
| Val 383 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 136015.5 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 5379.0 | |
| All* | Total formula weight | 141394.5 |
