8DHW

Treponema lecithinolyticum beta-glucuronidase in complex with a UNC4917-glucuronide conjugate

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Glycosyl hydrolase family 2, TIM barrel domain protein	polymer	631	72233.5	2	UniProt (U2KI81) UniProt (by SIFTS) (A0AA82WPE8)	Treponema lecithinolyticum	Beta-glucuronidase
2	C, I (A, B)	4-(4-beta-D-glucopyranuronosylpiperazin-1-yl)-2,7-bis(methylamino)pyrido[3',2':4,5]thieno[3,2-d]pyrimidine	non-polymer		505.5	2	Chemie (E0V)
3	D, E, F, G, H... (A, B)	SULFATE ION	non-polymer		96.1	11	Chemie (SO4)
4	P, Q (A, B)	water	water		18.0	918	Chemie (HOH)

Sequence modifications

A, B: 28 - 624 (UniProt: U2KI81)

PDB	External Database	Details
Met -6	-	initiating methionine
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag
Ser 1	-	expression tag
Ser 2	-	expression tag
Gly 3	-	expression tag
Val 4	-	expression tag
Asp 5	-	expression tag
Leu 6	-	expression tag
Gly 7	-	expression tag
Thr 8	-	expression tag
Glu 9	-	expression tag
Asn 10	-	expression tag
Leu 11	-	expression tag
Tyr 12	-	expression tag
Phe 13	-	expression tag
Gln 14	-	expression tag
Ser 15	-	expression tag
Asn 16	-	expression tag
Ala 17	-	expression tag
Met 18	-	expression tag
Leu 19	-	expression tag
Tyr 20	-	expression tag
Pro 21	-	expression tag
Ile 22	-	expression tag
Leu 23	-	expression tag
Thr 24	-	expression tag
Gln 25	-	expression tag
Ser 26	-	expression tag
Arg 27	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	144466.9
Non-Polymers*	Number of molecules	13
	Total formula weight	2067.8
All*	Total formula weight	146534.7

*Water molecules are not included.