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8DH6

Cryo-EM structure of Saccharomyces cerevisiae cytochrome c oxidase (Complex IV) extracted in lipid nanodiscs

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(a)
Cytochrome c oxidase subunit 1polymer53458832.61UniProt (P00401)
Pfam (PF00115)
Saccharomyces cerevisiae (baker's yeast)Cytochrome c oxidase polypeptide I
2B
(b)
Cytochrome c oxidase subunit 2polymer23626779.81UniProt (P00410)
Pfam (PF02790)
Pfam (PF00116)
Saccharomyces cerevisiae (baker's yeast)Cytochrome c oxidase polypeptide II
3C
(c)
Cytochrome c oxidase subunit 3polymer26930383.61UniProt (P00420)
Pfam (PF00510)
Saccharomyces cerevisiae (baker's yeast)Cytochrome c oxidase polypeptide III
4D
(d)
Cytochrome c oxidase subunit 4, mitochondrialpolymer13014188.91UniProt (P04037)
Pfam (PF01215)
Saccharomyces cerevisiae (baker's yeast)Cytochrome c oxidase polypeptide IV
5E
(e)
Cytochrome c oxidase subunit 5A, mitochondrialpolymer13314891.81UniProt (P00424)
Pfam (PF02936)
Saccharomyces cerevisiae (baker's yeast)Cytochrome c oxidase polypeptide Va
6F
(f)
Cytochrome c oxidase subunit 6, mitochondrialpolymer10812642.01UniProt (P00427)
Pfam (PF02284)
Saccharomyces cerevisiae (baker's yeast)Cytochrome c oxidase polypeptide VI
7G
(g)
Cytochrome c oxidase subunit 7, mitochondrialpolymer596811.21UniProt (P10174)
Pfam (PF02238)
Saccharomyces cerevisiae (baker's yeast)Cytochrome c oxidase polypeptide VII
8H
(h)
Cytochrome c oxidase subunit 8, mitochondrialpolymer515737.71UniProt (P04039)
Pfam (PF02935)
Saccharomyces cerevisiae (baker's yeast)Cytochrome c oxidase polypeptide VIII
9I
(i)
Cytochrome c oxidase subunit 9, mitochondrialpolymer556471.71UniProt (P07255)Saccharomyces cerevisiae (baker's yeast)Cytochrome c oxidase polypeptide VIIA
10J
(a)
CALCIUM IONnon-polymer40.11Chemie (CA)
11K
(a)
MAGNESIUM IONnon-polymer24.31Chemie (MG)
12L, S
(a, b)
COPPER (II) IONnon-polymer63.52Chemie (CU)
13M, N
(a)
HEME-Anon-polymer852.82Chemie (HEA)
14O, P, Q, R, T...
(a, b, c, e, g...)
DI-PALMITOYL-3-SN-PHOSPHATIDYLETHANOLAMINEnon-polymer692.010Chemie (PEF)
15W
(d)
ZINC IONnon-polymer65.41Chemie (ZN)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains9
Total formula weight176739.3
Non-Polymers*Number of molecules17
Total formula weight8882.1
All*Total formula weight185621.4
*Water molecules are not included.

246905

PDB entries from 2025-12-31

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