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8DH2

T7 RNA polymerase elongation complex with unnatural base dDs-ATP mismatch

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, E, I, L
(B, E, I, L)
T7 RNA polymerasepolymer88398984.24UniProt (P00573)
Pfam (PF14700)
Pfam (PF00940)
Escherichia phage T7DNA-directed RNA polymerase
2B, F, J, M
(A, F, J, M)
Template strand DNApolymer185616.74synthetic construct
3C, G, K, N
(C, G, K, N)
RNApolymer123851.44synthetic construct
4D, H, O
(D, H, O)
Non-template strand DNApolymer92666.83synthetic construct
5P, S, V
(B, C, I)
GLYCEROLnon-polymer92.13Chemie (GOL)
6Q, T, W, Y
(B, E, I, L)
TRIPHOSPHATEnon-polymer258.04Chemie (3PO)
7R, U, X, Z
(B, E, I, L)
MAGNESIUM IONnon-polymer24.34Chemie (MG)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains15
Total formula weight441809.5
Non-Polymers*Number of molecules11
Total formula weight1405.3
All*Total formula weight443214.9
*Water molecules are not included.

246031

PDB entries from 2025-12-10

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