8DE3
Native serotonin transporter in complex with 15B8 Fab antibody in the presence of cocaine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Transporter | polymer | 539 | 60778.9 | 1 | UniProt (A0A4X1TV69) Pfam (PF00209) UniProt (by SIFTS) (F1RN70) | Sus scrofa (pig) | |
| 2 | B (B) | 15B8 Fab heavy chain variable domain | polymer | 118 | 12980.5 | 1 | Mus musculus | ||
| 3 | C (C) | 15B8 Fab light chain variable domain | polymer | 110 | 11776.1 | 1 | Mus musculus | ||
| 4 | D (D) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
| 5 | E (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 6 | F, G (A) | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
| 7 | H (A) | COCAINE | non-polymer | 303.4 | 1 | Chemie (COC) | |||
| 8 | I, J (A) | CHOLESTEROL HEMISUCCINATE | non-polymer | 486.7 | 2 | Chemie (Y01) | |||
| 9 | K (A) | DODECYL-BETA-D-MALTOSIDE | non-polymer | 510.6 | 1 | Chemie (LMT) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 85535.5 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 424.4 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1868.9 | |
| All* | Total formula weight | 87828.7 |
