8DE3
Native serotonin transporter in complex with 15B8 Fab antibody in the presence of cocaine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Transporter | polymer | 539 | 60778.9 | 1 | UniProt (A0A4X1TV69) Pfam (PF00209) UniProt (by SIFTS) (F1RN70) | Sus scrofa (pig) | |
| 2 | B (B) | 15B8 Fab heavy chain variable domain | polymer | 118 | 12980.5 | 1 | Mus musculus | ||
| 3 | C (C) | 15B8 Fab light chain variable domain | polymer | 110 | 11776.1 | 1 | Mus musculus | ||
| 4 | D (D) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
| 5 | E (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) PubChem (312) | |||
| 6 | F, G (A) | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) PubChem (923) | |||
| 7 | H (A) | COCAINE | non-polymer | 303.4 | 1 | Chemie (COC) PubChem (2826) PubChem (5760) PubChem (44246523) PubChem (44281182) PubChem (44382114) PubChem (44382176) PubChem (44382277) PubChem (44382278) PubChem (122142) PubChem (135184) PubChem (50897619) PubChem (56840956) PubChem (165376) PubChem (44279116) PubChem (439497) PubChem (644005) PubChem (644017) PubChem (644018) PubChem (644271) PubChem (5872) PubChem (446220) PubChem (497304) PubChem (638023) PubChem (5315982) PubChem (6101676) PubChem (6338296) PubChem (6432459) PubChem (6432481) PubChem (98078900) PubChem (6918958) PubChem (9861246) PubChem (12305901) PubChem (10136514) PubChem (11779748) PubChem (13006129) PubChem (15558678) PubChem (15558680) PubChem (15558681) PubChem (15558688) PubChem (15558693) PubChem (124909386) PubChem (134972500) PubChem (173815154) | |||
| 8 | I, J (A) | CHOLESTEROL HEMISUCCINATE | non-polymer | 486.7 | 2 | Chemie (Y01) PubChem (16219150) PubChem (22210610) PubChem (65082) PubChem (45489984) PubChem (363416) PubChem (60078761) PubChem (500055) PubChem (73440805) PubChem (57163942) PubChem (89891013) PubChem (99567468) PubChem (124427194) PubChem (124897021) PubChem (124897020) PubChem (10005657) PubChem (130340716) PubChem (99567469) PubChem (11969853) PubChem (137392566) PubChem (137496323) PubChem (124301053) PubChem (124302591) PubChem (124303794) PubChem (124421343) PubChem (124427195) PubChem (13301926) PubChem (13301927) PubChem (124914595) PubChem (124914596) PubChem (155804219) PubChem (169132514) PubChem (131705526) PubChem (137332121) PubChem (137496357) PubChem (146157332) PubChem (154929912) PubChem (155199678) PubChem (156327905) PubChem (156426247) PubChem (156516588) PubChem (166979870) PubChem (167024614) PubChem (169132513) PubChem (170117245) PubChem (172400028) | |||
| 9 | K (A) | DODECYL-BETA-D-MALTOSIDE | non-polymer | 510.6 | 1 | Chemie (LMT) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 85535.5 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 424.4 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1868.9 | |
| All* | Total formula weight | 87828.7 |
