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8DDU

cryo-EM structure of TRPM3 ion channel in the presence of PIP2, state3

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, C, E, G
(A, B, C, D)
Transient receptor potential cation channel, subfamily M, member 3polymer1371157812.94UniProt (Q5F4S7)
Pfam (PF18139)
Pfam (PF25508)
Pfam (PF00520)
Pfam (PF16519)
UniProt (by SIFTS) (J9SQF3)
Mus musculus (house mouse)
2B, D, F, H
(E, F, G, H)
Unidentified segment at the N-terminus of TRPM3polymer171464.84Mus musculus
3I, N, Q, T
(A, B, C, D)
1,2-DIACYL-GLYCEROL-3-SN-PHOSPHATEnon-polymer705.04Chemie (3PH)
PubChem (86641)
PubChem (447938)
PubChem (16211043)
4J, O, R, U
(A, B, C, D)
(3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-ennon-polymer544.84Chemie (9Z9)
PubChem (134817783)
5K, P, S, V
(A, B, C, D)
[(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoatenon-polymer746.64Chemie (PIO)
PubChem (16219852)
PubChem (52946598)
PubChem (49867504)
PubChem (53394310)
PubChem (124587602)
PubChem (131850384)
PubChem (132274717)
PubChem (73441659)
PubChem (99649229)
PubChem (9543520)
PubChem (136212530)
PubChem (136212534)
6L, M
(A)
SODIUM IONnon-polymer23.02Chemie (NA)
PubChem (923)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains8
Total formula weight637110.9
Non-Polymers*Number of molecules14
Total formula weight8031.5
All*Total formula weight645142.3
*Water molecules are not included.

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PDB entries from 2026-03-25

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