8DCQ
CRYSTAL STRUCTURE OF HIV-1 LM/HT CLADE A/E CRF01 GP120 CORE IN COMPLEX WITH YIR-821
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | HIV-1 LM/HT Clade A/E CRF01 gp120 core | polymer | 355 | 39466.8 | 1 | UniProt (A0A0M3KKW9) | Human immunodeficiency virus 1 | |
| 2 | B, C, D, E, F... (A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 10 | Chemie (NAG) | |||
| 3 | L (A) | N~1~-{(3R)-1-[2-(5-carbamimidamidopentanamido)ethyl]-1-azaspiro[5.5]undecan-3-yl}-N~2~-(4-chlorophenyl)ethanediamide | non-polymer | 534.1 | 1 | Chemie (R5K) | |||
| 4 | M (A) | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID | non-polymer | 238.3 | 1 | Chemie (EPE) |
Sequence modifications
A: 44 - 492 (UniProt: A0A0M3KKW9)
| PDB | External Database | Details |
|---|---|---|
| Val 42 | - | expression tag |
| Pro 43 | - | expression tag |
| Tyr 61 | His 18 | engineered mutation |
| His 105 | Gln 62 | engineered mutation |
| Ile 108 | Val 65 | engineered mutation |
| Thr 375 | His 242 | engineered mutation |
| Asp 474 | Asn 335 | engineered mutation |
| Met 475 | Ile 336 | engineered mutation |
| Arg 476 | Lys 337 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 39466.8 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 2984.5 | |
| All* | Total formula weight | 42451.2 |
