8DBO
Human PRPS1-E307A engineered mutation with ADP; Hexamer
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Ribose-phosphate pyrophosphokinase 1 | polymer | 318 | 34777.1 | 6 | UniProt (P60891) Pfam (PF13793) Pfam (PF14572) | Homo sapiens (human) | PPRibP,Phosphoribosyl pyrophosphate synthase I,PRS-I |
| 2 | BA, G, GA, L, R... (E, A, F, B, C...) | PHOSPHATE ION | non-polymer | 95.0 | 6 | Chemie (PO4) | |||
| 3 | AA, CA, FA, H, HA... (E, F, A, B, C...) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 12 | Chemie (ADP) | |||
| 4 | DA, EA, I, IA, J... (E, A, F, B, C...) | MAGNESIUM ION | non-polymer | 24.3 | 12 | Chemie (MG) | |||
| 5 | KA, LA, MA, NA, OA... (A, B, C, D, E...) | water | water | 18.0 | 18 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F: 2 - 318 (UniProt: P60891)
| PDB | External Database | Details |
|---|---|---|
| Ser 1 | - | expression tag |
| Ala 307 | Glu 307 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 208662.5 | |
| Non-Polymers* | Number of molecules | 30 |
| Total formula weight | 5987.9 | |
| All* | Total formula weight | 214650.4 |
