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8D9D

Human DNA polymerase-alpha/primase elongation complex II bound to primer/template

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
DNA primase small subunitpolymer42049981.01UniProt (P49642)
Pfam (PF01896)
Homo sapiens (human)DNA primase 49 kDa subunit,p49
2B
(B)
DNA primase large subunitpolymer50958890.91UniProt (P49643)
Pfam (PF04104)
Homo sapiens (human)DNA primase 58 kDa subunit,p58
3C
(C)
DNA polymerase alpha catalytic subunitpolymer1462166131.11UniProt (P09884)
Pfam (PF12254)
Pfam (PF03104)
Pfam (PF00136)
Pfam (PF08996)
Homo sapiens (human)DNA polymerase alpha catalytic subunit p180
4D
(D)
DNA polymerase alpha subunit Bpolymer44449074.61UniProt (Q14181)
Pfam (PF22062)
Pfam (PF04042)
Homo sapiens (human)DNA polymerase alpha 70 kDa subunit
5E
(E)
DNA/RNA (5'-D(*(GTP))-R(P*GP*CP*GP*GP*CP*AP*CP*G)-D(P*AP*CP*C)-3')polymer123977.41Homo sapiens
6F
(F)
DNA (5'-D(*AP*TP*GP*GP*TP*CP*GP*TP*GP*CP*CP*GP*CP*CP*AP*AP*TP*AP*A)-3')polymer195829.81Homo sapiens
7G, J, K
(A, C)
ZINC IONnon-polymer65.43Chemie (ZN)
8H
(B)
IRON/SULFUR CLUSTERnon-polymer351.61Chemie (SF4)
9I, M
(C, E)
MAGNESIUM IONnon-polymer24.32Chemie (MG)
10L
(C)
2'-DEOXYADENOSINE 5'-TRIPHOSPHATEnon-polymer491.21Chemie (DTP)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains6
Total formula weight333884.8
Non-Polymers*Number of molecules7
Total formula weight1087.7
All*Total formula weight334972.4
*Water molecules are not included.

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PDB entries from 2025-06-18

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