8D9D

Human DNA polymerase-alpha/primase elongation complex II bound to primer/template

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	DNA primase small subunit	polymer	420	49981.0	1	UniProt (P49642) Pfam (PF01896) In PDB	Homo sapiens (human)	DNA primase 49 kDa subunit,p49
2	B	DNA primase large subunit	polymer	509	58890.9	1	UniProt (P49643) Pfam (PF04104) In PDB	Homo sapiens (human)	DNA primase 58 kDa subunit,p58
3	C	DNA polymerase alpha catalytic subunit	polymer	1462	166131.1	1	UniProt (P09884) Pfam (PF12254) Pfam (PF03104) Pfam (PF00136) Pfam (PF08996) In PDB	Homo sapiens (human)	DNA polymerase alpha catalytic subunit p180
4	D	DNA polymerase alpha subunit B	polymer	444	49074.6	1	UniProt (Q14181) Pfam (PF22062) Pfam (PF04042) In PDB	Homo sapiens (human)	DNA polymerase alpha 70 kDa subunit
5	E	DNA/RNA (5'-D(*(GTP))-R(P*GP*CP*GP*GP*CP*AP*CP*G)-D(P*AP*CP*C)-3')	polymer	12	3977.4	1		Homo sapiens
6	F	DNA (5'-D(*AP*TP*GP*GP*TP*CP*GP*TP*GP*CP*CP*GP*CP*CP*AP*AP*TP*AP*A)-3')	polymer	19	5829.8	1		Homo sapiens
7	A, C	ZINC ION	non-polymer		65.4	3	Chemie (ZN)
8	B	IRON/SULFUR CLUSTER	non-polymer		351.6	1	Chemie (SF4)
9	C, E	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)
10	C	2'-DEOXYADENOSINE 5'-TRIPHOSPHATE	non-polymer		491.2	1	Chemie (DTP)

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	333884.8
Non-Polymers*	Number of molecules	7
	Total formula weight	1087.7
All*	Total formula weight	334972.4

*Water molecules are not included.