8D8Q

SARS-CoV-2 Spike RBD in complex with DMAbs 2130 and 2196

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	H	2130 heavy chain	polymer	234	24834.9	1		Homo sapiens (Human)
2	L	2130 light chain	polymer	219	24077.7	1		Homo sapiens (Human)
3	A	Spike glycoprotein	polymer	1187	131573.7	1	UniProt (P0DTC2) Pfam (PF16451) Pfam (PF09408) Pfam (PF19209) Pfam (PF01601) In PDB	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)	S glycoprotein,E2,Peplomer protein
4	B	2196 light chain	polymer	216	23574.1	1		Homo sapiens (Human)
5	C	2196 heavy chain	polymer	226	24166.2	1		Homo sapiens (Human)
6	A	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	1	Chemie (NAG)

Sequence modifications

A: 16 - 1175 (UniProt: P0DTC2)

PDB	External Database	Details
Gly 1176	-	expression tag
Tyr 1177	-	expression tag
Ile 1178	-	expression tag
Pro 1179	-	expression tag
Glu 1180	-	expression tag
Ala 1181	-	expression tag
Pro 1182	-	expression tag
Arg 1183	-	expression tag
Asp 1184	-	expression tag
Gly 1185	-	expression tag
Gln 1186	-	expression tag
Ala 1187	-	expression tag
Tyr 1188	-	expression tag
Val 1189	-	expression tag
Arg 1190	-	expression tag
Lys 1191	-	expression tag
Asp 1192	-	expression tag
Gly 1193	-	expression tag
Glu 1194	-	expression tag
Trp 1195	-	expression tag
Val 1196	-	expression tag
Leu 1197	-	expression tag
Leu 1198	-	expression tag
Ser 1199	-	expression tag
Thr 1200	-	expression tag
Phe 1201	-	expression tag
Leu 1202	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	5
	Total formula weight	228226.6
Non-Polymers*	Number of molecules	1
	Total formula weight	221.2
All*	Total formula weight	228447.9

*Water molecules are not included.