8D7I
Bifunctional Inhibition of Neutrophil Elastase and Cathepsin G by Eap1 from S. aureus
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D, G, J, M... | Neutrophil elastase | polymer | 218 | 23319.0 | 6 | UniProt (P08246) Pfam (PF00089) In PDB | Homo sapiens (human) | Bone marrow serine protease, Elastase-2, Human leukocyte elastase, HLE, Medullasin, PMN elastase |
| 2 | B, E, H, K, N... | Extracellular Adherence Protein | polymer | 100 | 11185.6 | 6 | UniProt (Q99QS1) Pfam (PF03642) In PDB | Staphylococcus aureus subsp. aureus | Protein map |
| 3 | C, F, I, L, O... | Cathepsin G, C-terminal truncated form | polymer | 223 | 25397.1 | 6 | UniProt (P08311) Pfam (PF00089) In PDB | Homo sapiens (human) |
Sequence modifications
B, E, H, K, N, Q: 49 - 145 (UniProt: Q99QS1)
| PDB | External Database | Details |
|---|---|---|
| Gly 46 | - | expression tag |
| Ser 47 | - | expression tag |
| Thr 48 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 18 |
| Total formula weight | 359410.3 | |
| All* | Total formula weight | 359410.3 |
