8D3U

Human alpha3 Na+/K+-ATPase in its Na+-occluded state

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Sodium/potassium-transporting ATPase subunit alpha-3	polymer	1013	111864.3	1	UniProt (P13637) Pfam (PF00690) Pfam (PF00122) Pfam (PF13246) Pfam (PF00689)	Homo sapiens (human)	Na(+)/K(+) ATPase alpha-3 subunit,Na(+)/K(+) ATPase alpha(III) subunit,Sodium pump subunit alpha-3
2	B (B)	Sodium/potassium-transporting ATPase subunit beta-1	polymer	303	35108.3	1	UniProt (P05026) Pfam (PF00287)	Homo sapiens (human)	Sodium/potassium-dependent ATPase subunit beta-1
3	C (G)	FXYD domain-containing ion transport regulator 6	polymer	98	10855.6	1	UniProt (Q9H0Q3) Pfam (PF02038)	Homo sapiens (human)	Phosphohippolin
4	D (A)	ADENOSINE-5'-DIPHOSPHATE	non-polymer		427.2	1	Chemie (ADP)
5	E (A)	TETRAFLUOROALUMINATE ION	non-polymer		103.0	1	Chemie (ALF)

Sequence modifications

A: 18 - 1013 (UniProt: P13637)

PDB	External Database	Details
Met 1	-	initiating methionine
Gly 2	-	expression tag
Asp 3	-	expression tag
Lys 4	-	expression tag
Lys 5	-	expression tag
Asp 6	-	expression tag
Asp 7	-	expression tag
Lys 8	-	expression tag
Asp 9	-	expression tag
Ser 10	-	expression tag
Pro 11	-	expression tag
Lys 12	-	expression tag
Lys 13	-	expression tag
Asn 14	-	expression tag
Lys 15	-	expression tag
Gly 16	-	expression tag
Lys 17	-	expression tag

G: 1 - 95 (UniProt: Q9H0Q3)

PDB	External Database	Details
Met -2	-	initiating methionine
Ala -1	-	expression tag
Thr 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	157828.2
Non-Polymers*	Number of molecules	2
	Total formula weight	530.2
All*	Total formula weight	158358.4

*Water molecules are not included.