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8D3R

Human mitochondrial DNA polymerase gamma ternary complex with GT basepair in intermediate conformer

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
DNA polymerase subunit gamma-1polymer1239139730.71UniProt (P54098)
Pfam (PF18136)
Homo sapiens (human)Mitochondrial DNA polymerase catalytic subunit,PolG-alpha
2B, C
(B, C)
DNA polymerase subunit gamma-2, mitochondrialpolymer48554991.02UniProt (Q9UHN1)
Pfam (PF03129)
Homo sapiens (human)DNA polymerase gamma accessory 55 kDa subunit,p55,Mitochondrial DNA polymerase accessory subunit,MtPolB,PolG-beta
3D
(P)
DNA (5'-D(P*AP*AP*AP*AP*CP*GP*AP*CP*GP*GP*CP*CP*AP*GP*TP*GP*CP*CP*AP*TP*AP*T)-3')polymer247372.81synthetic construct
4E
(T)
DNA (5'-D(P*GP*GP*TP*AP*TP*GP*GP*CP*AP*CP*TP*GP*GP*CP*CP*GP*TP*CP*GP*TP*TP*TP*T)-3')polymer288644.51synthetic construct
5F
(A)
2'-DEOXYCYTIDINE-5'-TRIPHOSPHATEnon-polymer467.21Chemie (DCP)
6G
(A)
CALCIUM IONnon-polymer40.11Chemie (CA)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains5
Total formula weight265730.0
Non-Polymers*Number of molecules2
Total formula weight507.2
All*Total formula weight266237.3
*Water molecules are not included.

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PDB entries from 2026-01-14

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