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8D1E

hBest2 1uM Ca2+ (Ca2+-bound) closed state

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D, E
(D, E, C, A, B)
Bestrophin-2polymer40646796.95UniProt (Q8NFU1)
Pfam (PF01062)
Homo sapiens (human)Vitelliform macular dystrophy 2-like protein 1
2DB, EA, F, PA, R
(B, C, D, A, E)
CALCIUM IONnon-polymer40.15Chemie (CA)
3AA, AB, CA, CB, DA...
(E, A, B, C, D)
1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINEnon-polymer677.950Chemie (MC3)
4BA, NB, OA, P, ZA
(E, B, C, D, A)
2-[2-[(1~{S},2~{S},4~{S},5'~{R},6~{R},7~{S},8~{R},9~{S},12~{S},13~{R},16~{S})-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.0^{2,9}.0^{4,8}.0^{13,18}]icos-18-ene-6,2'-oxane]-16-yl]oxyethyl]propane-1,3-diolnon-polymer516.85Chemie (DU0)
5BB
(A)
CHLORIDE IONnon-polymer35.51Chemie (CL)
6OB, PB, QB, RB, SB
(D, E, C, A, B)
waterwater18.0629Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains5
Total formula weight233984.5
Non-Polymers*Number of molecules61
Total formula weight36716.3
All*Total formula weight270700.7
*Water molecules are not included.

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PDB entries from 2025-06-18

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