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8D0E

Human SARM1 TIR domain bound to NB-7

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
NAD(+) hydrolase SARM1polymer14316205.62UniProt (Q6SZW1)
Pfam (PF13676)
Homo sapiens (human)NADase SARM1,hSARM1,NADP(+) hydrolase SARM1,Sterile alpha and Armadillo repeat protein,Sterile alpha and TIR motif-containing protein 1,Sterile alpha motif domain-containing protein 2,MyD88-5,SAM domain-containing protein 2,Tir-1 homolog,HsTIR
2C, D
(A, B)
3-(4-chlorophenyl)-N-[4-methyl-3-(pyridin-4-yl)-1H-pyrazol-5-yl]propanamidenon-polymer340.82Chemie (Q0C)
3E, F
(A, B)
waterwater18.0215Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight32411.1
Non-Polymers*Number of molecules2
Total formula weight681.6
All*Total formula weight33092.8
*Water molecules are not included.

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PDB entries from 2025-06-18

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