8CXI

Structures of Zika Virus in Complex with Antibodies Targeting E Dimer Epitopes and Basis for Neutralization Efficacy

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C	Ankyrin repeat family A protein 2,Envelope E protein	polymer	639	69326.8	3	UniProt (Q9H9E1) UniProt (A0A142DS37) Pfam (PF00869) Pfam (PF02832) Pfam (PF21659) UniProt (by SIFTS) (A0A024B7W1) In PDB	Zika virus	RFXANK-like protein 2
2	D, E, F	Membrane M protein	polymer	3423	379600.7	3	UniProt (A0A1S6LXE0) Pfam (PF00948) Pfam (PF01005) Pfam (PF01002) Pfam (PF00949) Pfam (PF07652) Pfam (PF20907) Pfam (PF01350) Pfam (PF01349) Pfam (PF01728) Pfam (PF00972) Pfam (PF20483) Pfam (PF01003) Pfam (PF01570) Pfam (PF01004) Pfam (PF00869) Pfam (PF02832) Pfam (PF21659) UniProt (by SIFTS) (A0A024B7W1) In PDB	Zika virus
3	H, h	A11 heavy chain	polymer	133	14858.4	2		Homo sapiens
4	L, l	A11 light chain	polymer	111	11633.9	2		Homo sapiens
5	G, I	beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose	branched		732.7	2	In PDB GlyTouCan (G32152BH)

Sequence modifications

A, B, C: -134 - 0 (UniProt: Q9H9E1)
A, B, C: 1 - 504 (UniProt: A0A142DS37)

Contents of the asymmetric unit

Polymers	Number of chains	10
	Total formula weight	1399767.2
Branched	Number of molecules	2
	Total formula weight	1465.4
All*	Total formula weight	1401232.6

*Water molecules are not included.