8CWJ
Fab arms of antibodies 4C12-B12 and CR3022 bound to pangolin receptor binding domain (pRBD)
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | H, A | Heavy chain of CR3022 antibody Fab | polymer | 230 | 24428.4 | 2 | Homo sapiens (Human) | ||
2 | L, B | Light chain of CR3022 antibody Fab | polymer | 220 | 24289.9 | 2 | Homo sapiens (Human) | ||
3 | G, I | Spike glycoprotein | polymer | 204 | 22891.5 | 2 | UniProt (A0A7D6TQ96) Pfam (PF09408) UniProt (by SIFTS) (A0A7D6PMV8) In PDB | Pangolin coronavirus | S glycoprotein,E2,Peplomer protein |
4 | J, U | Heavy chain of 4C12-B12 antibody Fab | polymer | 230 | 24514.2 | 2 | Homo sapiens (Human) | ||
5 | K, V | Light chain of 4C12-B12 antibody Fab | polymer | 215 | 23466.1 | 2 | Homo sapiens (Human) | ||
6 | C, D, E | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 570.5 | 3 | In PDB GlyTouCan (G21290RB) | |||
7 | J, K, U, V, H... | GLYCEROL | non-polymer | 92.1 | 15 | Chemie (GOL) | |||
8 | G | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
9 | I, J, K, U, G | CHLORIDE ION | non-polymer | 35.5 | 10 | Chemie (CL) | |||
10 | water | water | 18.0 | 363 | Chemie (HOH) |
Sequence modifications
G, I: 333 - 528 (UniProt: A0A7D6TQ96)
PDB | External Database | Details |
---|---|---|
Gly 420 | Asp 416 | conflict |
Gly 529 | - | expression tag |
Ser 530 | - | expression tag |
His 531 | - | expression tag |
His 532 | - | expression tag |
His 533 | - | expression tag |
His 534 | - | expression tag |
His 535 | - | expression tag |
His 536 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 10 |
Total formula weight | 239180.3 | |
Branched | Number of molecules | 3 |
Total formula weight | 1711.6 | |
Non-Polymers* | Number of molecules | 26 |
Total formula weight | 1957.1 | |
All* | Total formula weight | 242849.1 |