8CVM
Cutibacterium acnes 50S ribosomal subunit with P-site tRNA and Sarecycline bound in the local refined map
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (c) | 50S ribosomal protein L2 | polymer | 278 | 30309.9 | 1 | UniProt (A0A2B7JMV5) Pfam (PF00181) Pfam (PF03947) UniProt (by SIFTS) (Q6A6M9) | Cutibacterium acnes | |
| 2 | B (d) | 50S ribosomal protein L3 | polymer | 223 | 23553.1 | 1 | UniProt (A0A085B5E3) Pfam (PF00297) UniProt (by SIFTS) (Q6A6M6) | Cutibacterium acnes | |
| 3 | C (e) | 50S ribosomal protein L4 | polymer | 301 | 32342.2 | 1 | UniProt (A0A2B7I5M5) Pfam (PF00573) UniProt (by SIFTS) (Q6A6M7) | Cutibacterium acnes | |
| 4 | D (f) | 50S ribosomal protein L5 | polymer | 210 | 23901.8 | 1 | UniProt (A0A3E2DDM1) Pfam (PF00281) Pfam (PF00673) UniProt (by SIFTS) (Q6A6N8) | Cutibacterium acnes | |
| 5 | E (g) | 50S ribosomal protein L6 | polymer | 180 | 19868.8 | 1 | UniProt (A0A2B7I5S3) Pfam (PF00347) UniProt (by SIFTS) (Q6A6P1) | Cutibacterium acnes | |
| 6 | F (i) | 50S ribosomal protein L13 | polymer | 147 | 16325.8 | 1 | UniProt (A0A2B7I6I7) Pfam (PF00572) UniProt (by SIFTS) (Q6A6T3) | Cutibacterium acnes | |
| 7 | G (j) | 50S ribosomal protein L14 | polymer | 122 | 13503.9 | 1 | UniProt (A0A2B7JMZ8) Pfam (PF00238) UniProt (by SIFTS) (Q6A6N6) | Cutibacterium acnes | |
| 8 | H (k) | 50S ribosomal protein L15 | polymer | 146 | 15542.9 | 1 | UniProt (A0A2B7IUA0) Pfam (PF00828) UniProt (by SIFTS) (Q6A6P5) | Cutibacterium acnes | |
| 9 | I (l) | 50S ribosomal protein L16 | polymer | 139 | 15700.2 | 1 | UniProt (A0A2B7I5M8) Pfam (PF00252) UniProt (by SIFTS) (Q6A6N3) | Cutibacterium acnes | |
| 10 | J (m) | 50S ribosomal protein L17 | polymer | 187 | 20058.6 | 1 | UniProt (A0A085AZY3) Pfam (PF01196) UniProt (by SIFTS) (Q6A6R2) | Cutibacterium acnes | |
| 11 | K (n) | 50S ribosomal protein L18 | polymer | 127 | 13727.8 | 1 | UniProt (A0A2B7JN02) Pfam (PF00861) UniProt (by SIFTS) (Q6A6P2) | Cutibacterium acnes | |
| 12 | L (o) | 50S ribosomal protein L19 | polymer | 117 | 13106.1 | 1 | UniProt (A0A2C6LKT3) Pfam (PF01245) UniProt (by SIFTS) (Q6A7T1) | Cutibacterium acnes | |
| 13 | M (p) | 50S ribosomal protein L20 | polymer | 123 | 13988.0 | 1 | UniProt (A0A2B7I6V3) Pfam (PF00453) UniProt (by SIFTS) (Q6A7V3) | Cutibacterium acnes | |
| 14 | N (q) | 50S ribosomal protein L21 | polymer | 102 | 11087.8 | 1 | UniProt (A0A085B4N9) Pfam (PF00829) UniProt (by SIFTS) (Q6A9I3) | Cutibacterium acnes | |
| 15 | O (r) | 50S ribosomal protein L22 | polymer | 153 | 16729.5 | 1 | UniProt (A0A2B7ITY5) Pfam (PF00237) UniProt (by SIFTS) (Q6A6N1) | Cutibacterium acnes | |
| 16 | P (s) | 50S ribosomal protein L23 | polymer | 102 | 11349.2 | 1 | UniProt (A0A2C6LEQ5) Pfam (PF00276) UniProt (by SIFTS) (Q6A6M8) | Cutibacterium acnes | |
| 17 | Q (t) | 50S ribosomal protein L24 | polymer | 122 | 13514.6 | 1 | UniProt (A0A085B5D2) Pfam (PF00467) Pfam (PF17136) UniProt (by SIFTS) (Q6A6N7) | Cutibacterium acnes | |
| 18 | R (u) | 50S ribosomal protein L25 | polymer | 205 | 22349.1 | 1 | UniProt (A0A2B7IYF8) Pfam (PF01386) Pfam (PF14693) UniProt (by SIFTS) (Q6AAC8) | Cutibacterium acnes | General stress protein CTC |
| 19 | S (v) | 50S ribosomal protein L27 | polymer | 89 | 9540.7 | 1 | UniProt (A0A2B7IGT1) Pfam (PF01016) UniProt (by SIFTS) (Q6A9I2) | Cutibacterium acnes | |
| 20 | T (w) | 50S ribosomal protein L28 | polymer | 61 | 6953.2 | 1 | UniProt (A0A2B7I7B7) Pfam (PF00830) | Cutibacterium acnes | |
| 21 | U (x) | 50S ribosomal protein L29 | polymer | 77 | 8899.1 | 1 | UniProt (A0A2B7JB12) Pfam (PF00831) UniProt (by SIFTS) (Q6A6N4) | Cutibacterium acnes | |
| 22 | V (y) | 50S ribosomal protein L30 | polymer | 60 | 6932.2 | 1 | UniProt (A0A2B7I5Y4) Pfam (PF00327) UniProt (by SIFTS) (Q6A6P4) | Cutibacterium acnes | |
| 23 | W (z) | 50S ribosomal protein L32 | polymer | 63 | 6991.1 | 1 | UniProt (A0A2B7I771) Pfam (PF01783) | Cutibacterium acnes | |
| 24 | X (0) | 50S ribosomal protein L33 | polymer | 56 | 6725.9 | 1 | UniProt (A0A2C6LJM0) Pfam (PF00471) UniProt (by SIFTS) (Q6A6J5) | Cutibacterium acnes | |
| 25 | Y (1) | 50S ribosomal protein L34 | polymer | 44 | 5185.1 | 1 | UniProt (A0A2B7IDI8) Pfam (PF00468) UniProt (by SIFTS) (Q6A5A1) | Cutibacterium acnes | |
| 26 | Z (2) | 50S ribosomal protein L35 | polymer | 68 | 7457.9 | 1 | UniProt (A0A085AZG2) Pfam (PF01632) UniProt (by SIFTS) (Q6A7V2) | Cutibacterium acnes | |
| 27 | AA (4) | 50S ribosomal protein L31 | polymer | 69 | 7731.8 | 1 | UniProt (A0A2B7JUW7) Pfam (PF01197) UniProt (by SIFTS) (Q6A8B4) | Cutibacterium acnes | |
| 28 | BA (a) | 23S ribosomal RNA | polymer | 3086 | 1002554.6 | 1 | Cutibacterium acnes | ||
| 29 | CA (b) | 5S ribosomal RNA | polymer | 120 | 38770.1 | 1 | GenBank (2179609306) | Cutibacterium acnes | |
| 30 | DA (V) | 50S ribosomal protein bL37 | polymer | 24 | 2744.3 | 1 | Cutibacterium acnes | ||
| 31 | EA (C) | Initiator fMet RNA | polymer | 77 | 24846.9 | 1 | GenBank (732678099) | Escherichia coli | |
| 32 | FA (3) | 50S ribosomal protein L36 | polymer | 37 | 4386.4 | 1 | UniProt (A0A2B7JN22) Pfam (PF00444) UniProt (by SIFTS) (Q6A6Q7) | Cutibacterium acnes | |
| 33 | AB, AC, AD, AE, AF... (a, b, C, c, d...) | MAGNESIUM ION | non-polymer | 24.3 | 305 | Chemie (MG) | |||
| 34 | MA, NA, OA, QA (w, z, 0, 4) | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
| 35 | RA (a) | Sarecycline | non-polymer | 487.5 | 1 | Chemie (V7A) | |||
| 36 | EM, FM, GM, HM (d, s, a, b) | water | water | 18.0 | 125 | Chemie (HOH) |
Sequence modifications
m: 1 - 187 (UniProt: A0A085AZY3)
| PDB | External Database | Details |
|---|---|---|
| Ile 102 | Asn 102 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 32 |
| Total formula weight | 1466678.5 | |
| Non-Polymers* | Number of molecules | 310 |
| Total formula weight | 8162.2 | |
| All* | Total formula weight | 1474840.6 |
