8CUK

X-ray Structure of the WD40 domain of HOPS subunit Vps11 from Yeast

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C (A, B, C)	E3 ubiquitin-protein ligase PEP5	polymer	379	42355.4	3	UniProt (P12868) Pfam (PF23341)	Saccharomyces cerevisiae (baker's yeast)	Carboxypeptidase Y-deficient protein 5,Histone E3 ligase PEP5,RING-type E3 ubiquitin transferase PEP5,Vacuolar biogenesis protein END1,Vacuolar morphogenesis protein 1,Vacuolar protein sorting-associated protein 11,Vacuolar protein-targeting protein 11
2	D, E, F (A, B, C)	water	water		18.0	392	Chemie (HOH)

Sequence modifications

A, B, C: 1 - 350 (UniProt: P12868)

PDB	External Database	Details
Met -28	-	initiating methionine
Lys -27	-	expression tag
His -26	-	expression tag
His -25	-	expression tag
His -24	-	expression tag
His -23	-	expression tag
His -22	-	expression tag
His -21	-	expression tag
His -20	-	expression tag
Gly -19	-	expression tag
Ala -18	-	expression tag
Ala -17	-	expression tag
Gly -16	-	expression tag
Thr -15	-	expression tag
Ser -14	-	expression tag
Leu -13	-	expression tag
Tyr -12	-	expression tag
Lys -11	-	expression tag
Lys -10	-	expression tag
Ala -9	-	expression tag
Gly -8	-	expression tag
Glu -7	-	expression tag
Asn -6	-	expression tag
Leu -5	-	expression tag
Tyr -4	-	expression tag
Phe -3	-	expression tag
Gln -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	127066.1
All*	Total formula weight	127066.1

*Water molecules are not included.