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8CUA

Human excitatory amino acid transporter 3 (EAAT3) with bound potassium in an intermediate outward facing state

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C
(A, B, C)
Excitatory amino acid transporter 3polymer52657120.93UniProt (P43005)
Pfam (PF00375)
Homo sapiens (human)Excitatory amino-acid carrier 1,Neuronal and epithelial glutamate transporter,Sodium-dependent glutamate/aspartate transporter 3,Solute carrier family 1 member 1
2D, F, H
(A, B, C)
POTASSIUM IONnon-polymer39.13Chemie (K)
3E, G, I
(A, B, C)
MERCURY (II) IONnon-polymer200.63Chemie (HG)
4J, K, L
(A, B, C)
waterwater18.030Chemie (HOH)
Sequence modifications
A, B, C: 1 - 524 (UniProt: P43005)
PDBExternal DatabaseDetails
Gly -1-expression tag
Pro 0-expression tag
Ala 9Cys 9conflict
Ala 100Cys 100conflict
Ala 158Cys 158conflict
Thr 178Asn 178conflict
Thr 195Asn 195conflict
Ala 219Cys 219conflict
Trp 256Cys 256conflict
Cys 269Lys 269conflict
Cys 441Trp 441conflict
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight171362.6
Non-Polymers*Number of molecules6
Total formula weight719.1
All*Total formula weight172081.7
*Water molecules are not included.

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PDB entries from 2025-07-09

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