8CT8

Crystal structure of Drosophila melanogaster PRL/CBS-pair domain complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Unextended protein	polymer	161	18183.4	2	UniProt (A0A0B7P9G0) In PDB	Drosophila melanogaster (fruit fly)	Putative metal transporter uex
2	C, D	PRL-1 phosphatase	polymer	161	18455.3	2	UniProt (O61722) Pfam (PF22785) In PDB	Drosophila melanogaster (fruit fly)	Phosphatase of regenerating liver-1
3	A, C, D	IODIDE ION	non-polymer		126.9	3	Chemie (IOD)
4		water	water		18.0	54	Chemie (HOH)

Sequence modifications

A, B: 362 - 515 (UniProt: A0A0B7P9G0)

PDB	External Database	Details
Gly 357	-	expression tag
Pro 358	-	expression tag
Leu 359	-	expression tag
Gly 360	-	expression tag
Ser 361	-	expression tag
Leu 516	-	expression tag
Glu 517	-	expression tag

C, D: 14 - 165 (UniProt: O61722)

PDB	External Database	Details
Met 13	-	initiating methionine
Ala 104	Cys 104	engineered mutation
Leu 166	-	expression tag
Glu 167	-	expression tag
His 168	-	expression tag
His 169	-	expression tag
His 170	-	expression tag
His 171	-	expression tag
His 172	-	expression tag
His 173	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	73277.5
Non-Polymers*	Number of molecules	3
	Total formula weight	380.7
All*	Total formula weight	73658.2

*Water molecules are not included.