8CRX
Cutibacterium acnes 70S ribosome with mRNA, P-site tRNA and Sarecycline bound
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | RNA (1537-MER) | polymer | 1537 | 498742.9 | 1 | GenBank (2179609306) | Cutibacterium acnes | |
| 2 | B (D) | 30S ribosomal protein S4 | polymer | 201 | 23271.6 | 1 | UniProt (A0A2B7JMY9) Pfam (PF00163) Pfam (PF01479) UniProt (by SIFTS) (Q6A6R0) | Cutibacterium acnes | |
| 3 | C (E) | 30S ribosomal protein S5 | polymer | 215 | 22603.7 | 1 | UniProt (A0A2B7I5L8) Pfam (PF03719) Pfam (PF00333) UniProt (by SIFTS) (Q6A6P3) | Cutibacterium acnes | |
| 4 | D (F) | 30S ribosomal protein S6 | polymer | 96 | 11270.1 | 1 | UniProt (A0A2C6L3A1) Pfam (PF01250) UniProt (by SIFTS) (Q6A5M9) | Cutibacterium acnes | |
| 5 | E (H) | 30S ribosomal protein S8 | polymer | 135 | 14677.9 | 1 | UniProt (A0A2B7ITQ7) Pfam (PF00410) UniProt (by SIFTS) (Q6A6P0) | Cutibacterium acnes | |
| 6 | F (K) | 30S ribosomal protein S11 | polymer | 135 | 14194.5 | 1 | UniProt (A0A2B7I645) Pfam (PF00411) UniProt (by SIFTS) (Q6A6Q9) | Cutibacterium acnes | |
| 7 | G (L) | 30S ribosomal protein S12 | polymer | 123 | 13666.1 | 1 | UniProt (A0A2C6LJN0) Pfam (PF00164) UniProt (by SIFTS) (Q6A6L2) | Cutibacterium acnes | |
| 8 | H (O) | 30S ribosomal protein S15 | polymer | 87 | 10102.8 | 1 | UniProt (A0A2B7I743) Pfam (PF00312) UniProt (by SIFTS) (Q6A7P5) | Cutibacterium acnes | |
| 9 | I (Q) | 30S ribosomal protein S17 | polymer | 90 | 10475.3 | 1 | UniProt (A0A2B7JMS7) Pfam (PF00366) UniProt (by SIFTS) (Q6A6N5) | Cutibacterium acnes | |
| 10 | J (R) | 30S ribosomal protein S18 | polymer | 79 | 8817.5 | 1 | UniProt (A0A2C6LI71) Pfam (PF01084) UniProt (by SIFTS) (Q6A5N1) | Cutibacterium acnes | |
| 11 | K (T) | 30S ribosomal protein S20 | polymer | 88 | 9724.3 | 1 | UniProt (A0A2B7I592) Pfam (PF01649) UniProt (by SIFTS) (Q6A9B3) | Cutibacterium acnes | |
| 12 | L (P) | 30S ribosomal protein S16 | polymer | 147 | 15980.9 | 1 | UniProt (A0A2B7IXM7) Pfam (PF00886) UniProt (by SIFTS) (Q6A7S4) | Cutibacterium acnes | |
| 13 | M (X) | 30S ribosomal protein bS22 | polymer | 33 | 4120.2 | 1 | UniProt (A0A533INE0) Pfam (PF08213) UniProt (by SIFTS) (Q6AAZ0) | Cutibacterium acnes | AURKAIP1/COX24 domain-containing protein |
| 14 | N (G) | 30S ribosomal protein S3 | polymer | 269 | 29728.7 | 1 | UniProt (A0A2B7I5Y3) Pfam (PF07650) Pfam (PF00189) UniProt (by SIFTS) (Q6A6N2) | Cutibacterium acnes | |
| 15 | O (I) | 30S ribosomal protein S7 | polymer | 156 | 17615.5 | 1 | UniProt (A0A2B7ITZ4) Pfam (PF00177) UniProt (by SIFTS) (Q6A6L4) | Cutibacterium acnes | |
| 16 | P (J) | 30S ribosomal protein S9 | polymer | 173 | 18630.1 | 1 | UniProt (A0A2B7JN42) Pfam (PF00380) | Cutibacterium acnes | |
| 17 | Q (M) | 30S ribosomal protein S10 | polymer | 103 | 11750.8 | 1 | UniProt (A0A085B5E4) Pfam (PF00338) UniProt (by SIFTS) (Q6A6M5) | Cutibacterium acnes | |
| 18 | R (N) | 30S ribosomal protein S13 | polymer | 123 | 14030.2 | 1 | UniProt (A0A2C6LKT6) Pfam (PF00416) UniProt (by SIFTS) (Q6A6Q8) | Cutibacterium acnes | |
| 19 | S (S) | 30S ribosomal protein S14 type Z | polymer | 61 | 6924.4 | 1 | UniProt (A0A2B7JMX1) Pfam (PF00253) UniProt (by SIFTS) (Q6A6N9) | Cutibacterium acnes | |
| 20 | T (U) | 30S ribosomal protein S19 | polymer | 93 | 10536.3 | 1 | UniProt (A0A2B7ITR7) Pfam (PF00203) UniProt (by SIFTS) (Q6A6N0) | Cutibacterium acnes | |
| 21 | U (B) | 30S ribosomal protein S2 | polymer | 283 | 31583.2 | 1 | UniProt (A0A2B7I756) Pfam (PF00318) UniProt (by SIFTS) (Q6A7J7) | Cutibacterium acnes | |
| 22 | V (c) | 50S ribosomal protein L2 | polymer | 278 | 30309.9 | 1 | UniProt (A0A2B7JMV5) Pfam (PF00181) Pfam (PF03947) UniProt (by SIFTS) (Q6A6M9) | Cutibacterium acnes | |
| 23 | W (d) | 50S ribosomal protein L3 | polymer | 223 | 23553.1 | 1 | UniProt (A0A1G9KW65) Pfam (PF00297) UniProt (by SIFTS) (Q6A6M6) | Cutibacterium acnes | |
| 24 | X (e) | 50S ribosomal protein L4 | polymer | 301 | 32342.2 | 1 | UniProt (A0A2B7I5M5) Pfam (PF00573) | Cutibacterium acnes | |
| 25 | Y (f) | 50S ribosomal protein L5 | polymer | 210 | 23901.8 | 1 | UniProt (A0A3E2DDM1) Pfam (PF00281) Pfam (PF00673) | Cutibacterium acnes | |
| 26 | Z (g) | 50S ribosomal protein L6 | polymer | 180 | 19868.8 | 1 | UniProt (A0A2B7I5S3) Pfam (PF00347) UniProt (by SIFTS) (Q6A6P1) | Cutibacterium acnes | |
| 27 | AA (i) | 50S ribosomal protein L13 | polymer | 147 | 16325.8 | 1 | UniProt (A0A2B7I6I7) Pfam (PF00572) | Cutibacterium acnes | |
| 28 | BA (j) | 50S ribosomal protein L14 | polymer | 122 | 13503.9 | 1 | UniProt (A0A2B7JMZ8) Pfam (PF00238) | Cutibacterium acnes | |
| 29 | CA (k) | 50S ribosomal protein L15 | polymer | 146 | 15542.9 | 1 | UniProt (A0A2B7IUA0) Pfam (PF00828) UniProt (by SIFTS) (Q6A6P5) | Cutibacterium acnes | |
| 30 | DA (l) | 50S ribosomal protein L16 | polymer | 139 | 15700.2 | 1 | UniProt (A0A2B7I5M8) Pfam (PF00252) UniProt (by SIFTS) (Q6A6N3) | Cutibacterium acnes | |
| 31 | EA (m) | 50S ribosomal protein L17 | polymer | 187 | 20058.6 | 1 | UniProt (A0A085AZY3) Pfam (PF01196) UniProt (by SIFTS) (A0A8B2VJI7) | Cutibacterium acnes | |
| 32 | FA (n) | 50S ribosomal protein L18 | polymer | 127 | 13727.8 | 1 | UniProt (A0A2B7JN02) Pfam (PF00861) UniProt (by SIFTS) (Q6A6P2) | Cutibacterium acnes | |
| 33 | GA (o) | 50S ribosomal protein L19 | polymer | 117 | 13106.1 | 1 | UniProt (A0A2C6LKT3) Pfam (PF01245) UniProt (by SIFTS) (Q6A7T1) | Cutibacterium acnes | |
| 34 | HA (p) | 50S ribosomal protein L20 | polymer | 123 | 13988.0 | 1 | UniProt (A0A2B7I6V3) Pfam (PF00453) UniProt (by SIFTS) (Q6A7V3) | Cutibacterium acnes | |
| 35 | IA (q) | 50S ribosomal protein L21 | polymer | 102 | 11087.8 | 1 | UniProt (A0A085B4N9) Pfam (PF00829) UniProt (by SIFTS) (Q6A9I3) | Cutibacterium acnes | |
| 36 | JA (r) | 50S ribosomal protein L22 | polymer | 153 | 16729.5 | 1 | UniProt (A0A2B7ITY5) Pfam (PF00237) UniProt (by SIFTS) (Q6A6N1) | Cutibacterium acnes | |
| 37 | KA (s) | 50S ribosomal protein L23 | polymer | 102 | 11349.2 | 1 | UniProt (A0A2C6LEQ5) Pfam (PF00276) UniProt (by SIFTS) (Q6A6M8) | Cutibacterium acnes | |
| 38 | LA (t) | 50S ribosomal protein L24 | polymer | 122 | 13514.6 | 1 | UniProt (A0A085B5D2) Pfam (PF00467) Pfam (PF17136) UniProt (by SIFTS) (Q6A6N7) | Cutibacterium acnes | |
| 39 | MA (u) | 50S ribosomal protein L25 | polymer | 205 | 22349.1 | 1 | UniProt (A0A2B7IYF8) Pfam (PF01386) Pfam (PF14693) UniProt (by SIFTS) (Q6AAC8) | Cutibacterium acnes | General stress protein CTC |
| 40 | NA (v) | 50S ribosomal protein L27 | polymer | 89 | 9540.7 | 1 | UniProt (A0A2B7IGT1) Pfam (PF01016) UniProt (by SIFTS) (Q6A9I2) | Cutibacterium acnes | |
| 41 | OA (w) | 50S ribosomal protein L28 | polymer | 61 | 6953.2 | 1 | UniProt (A0A2B7I7B7) Pfam (PF00830) | Cutibacterium acnes | |
| 42 | PA (x) | 50S ribosomal protein L29 | polymer | 77 | 8899.1 | 1 | UniProt (A0A2B7JB12) Pfam (PF00831) UniProt (by SIFTS) (Q6A6N4) | Cutibacterium acnes | |
| 43 | QA (y) | 50S ribosomal protein L30 | polymer | 60 | 6932.2 | 1 | UniProt (A0A2B7I5Y4) Pfam (PF00327) UniProt (by SIFTS) (Q6A6P4) | Cutibacterium acnes | |
| 44 | RA (z) | 50S ribosomal protein L32 | polymer | 63 | 6991.1 | 1 | UniProt (A0A2B7I771) Pfam (PF01783) | Cutibacterium acnes | |
| 45 | SA (0) | 50S ribosomal protein L33 | polymer | 56 | 6725.9 | 1 | UniProt (A0A2C6LJM0) Pfam (PF00471) UniProt (by SIFTS) (Q6A6J5) | Cutibacterium acnes | |
| 46 | TA (1) | 50S ribosomal protein L34 | polymer | 44 | 5185.1 | 1 | UniProt (A0A2B7IDI8) Pfam (PF00468) UniProt (by SIFTS) (Q6A5A1) | Cutibacterium acnes | |
| 47 | UA (2) | 50S ribosomal protein L35 | polymer | 68 | 7457.9 | 1 | UniProt (A0A371N4N9) Pfam (PF01632) UniProt (by SIFTS) (Q6A7V2) | Cutibacterium acnes | |
| 48 | VA (4) | 50S ribosomal protein L31 | polymer | 69 | 7731.8 | 1 | UniProt (A0A2B7JUW7) Pfam (PF01197) UniProt (by SIFTS) (Q6A8B4) | Cutibacterium acnes | |
| 49 | WA (a) | 23S ribosomal RNA | polymer | 3086 | 1002554.6 | 1 | Cutibacterium acnes | ||
| 50 | XA (b) | 5S ribosomal RNA | polymer | 120 | 38770.1 | 1 | GenBank (2179609306) | Cutibacterium acnes | |
| 51 | YA (V) | 50S ribosomal protein bL37 | polymer | 24 | 2744.3 | 1 | UniProt (by SIFTS) (A0A9Y2YAG1) | Cutibacterium acnes | |
| 52 | ZA (Y) | 32MF mRNA | polymer | 22 | 7115.3 | 1 | Escherichia coli | ||
| 53 | AB (C) | P-site initiator tRNA | polymer | 77 | 24846.9 | 1 | GenBank (732678099) | Escherichia coli | |
| 54 | BB (3) | 50S ribosomal protein L36 | polymer | 37 | 4386.4 | 1 | UniProt (A0A2B7JN22) Pfam (PF00444) UniProt (by SIFTS) (Q6A6Q7) | Cutibacterium acnes | |
| 55 | CB, TE (A, a) | Sarecycline | non-polymer | 487.5 | 2 | Chemie (V7A) | |||
| 56 | AC, AD, AE, AF, AG... (A, a, b, C, c...) | MAGNESIUM ION | non-polymer | 24.3 | 386 | Chemie (MG) | |||
| 57 | HE, OE, PE, QE, SE (S, w, z, 0, 4) | ZINC ION | non-polymer | 65.4 | 5 | Chemie (ZN) | |||
| 58 | FQ, GQ, HQ, IQ, JQ (A, d, s, a, b) | water | water | 18.0 | 129 | Chemie (HOH) |
Sequence modifications
m: 1 - 187 (UniProt: A0A085AZY3)
| PDB | External Database | Details |
|---|---|---|
| Ile 102 | Asn 102 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 54 |
| Total formula weight | 2272240.6 | |
| Non-Polymers* | Number of molecules | 393 |
| Total formula weight | 10683.8 | |
| All* | Total formula weight | 2282924.4 |
