8CRC
Structure of human Plk1 PBD in complex with Allopole-A
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Serine/threonine-protein kinase PLK1 | polymer | 228 | 26368.1 | 1 | UniProt (P53350) Pfam (PF00659) In PDB | Homo sapiens (human) | Polo-like kinase 1,PLK-1,Serine/threonine-protein kinase 13,STPK13 |
| 2 | A | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 3 | A | 7-chloro-4-(cyclopropylmethyl)-1-thioxo-2,4-dihydrothieno[2,3-e][1,2,4]triazolo[4,3-a]pyrimidin-5(1H)-one | non-polymer | 312.8 | 1 | Chemie (VIH) | |||
| 4 | water | water | 18.0 | 180 | Chemie (HOH) |
Sequence modifications
A: 371 - 594 (UniProt: P53350)
| PDB | External Database | Details |
|---|---|---|
| Gly 367 | - | expression tag |
| Ala 368 | - | expression tag |
| His 369 | - | expression tag |
| Met 370 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 26368.1 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 404.9 | |
| All* | Total formula weight | 26773.0 |
