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8CR2

Homo sapiens Get1/Get2 heterotetramer (a3' deletion variant) in complex with a Get3 dimer

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, BATPase ASNA1polymer36040146.12UniProt (O43681)
Pfam (PF02374)
In PDB
Homo sapiens (human)Arsenical pump-driving ATPase,Arsenite-stimulated ATPase,Transmembrane domain recognition complex 40 kDa ATPase subunit,hARSA-I,hASNA-I
2C, DGuided entry of tail-anchored proteins factor CAMLG,Guided entry of tail-anchored proteins factor 1polymer30634429.42UniProt (P49069)
UniProt (O00258)
Pfam (PF14963)
Pfam (PF04420)
In PDB
Homo sapiens (human)Calcium signal-modulating cyclophilin ligand,Congenital heart disease 5 protein,Tail-anchored protein insertion receptor WRB,Tryptophan-rich basic protein
3BZINC IONnon-polymer65.41Chemie (ZN)
Sequence modifications
A, B: 1 - 348 (UniProt: O43681)
PDBExternal DatabaseDetails
Gly -1-expression tag
Ala 0-expression tag
Gly 349-expression tag
Ser 350-expression tag
Trp 351-expression tag
Ser 352-expression tag
His 353-expression tag
Pro 354-expression tag
Gln 355-expression tag
Phe 356-expression tag
Glu 357-expression tag
Lys 358-expression tag
C, D: 186 - 241 (UniProt: P49069)
PDBExternal DatabaseDetails
Met 185-initiating methionine
C, D: 251 - 296 (UniProt: P49069)
PDBExternal DatabaseDetails
Gly 242-linker
Gly 243-linker
Gly 244-linker
Gly 245-linker
Gly 297-linker
Ser 298-linker
Gly 299-linker
Ser 300-linker
Glu 301-linker
Asn 302-linker
Leu 303-linker
Tyr 304-linker
Phe 305-linker
Gln 306-linker
Ser 307-linker
Gly 308-linker
Ser 309-linker
Gly 310-linker
Ser 311-linker
C, D: 1001 - 1174 (UniProt: O00258)
PDBExternal DatabaseDetails
Gly 1175-expression tag
Ser 1176-expression tag
Gly 1177-expression tag
Ser 1178-expression tag
Leu 1179-expression tag
Glu 1180-expression tag
Val 1181-expression tag
Leu 1182-expression tag
Phe 1183-expression tag
Gln 1184-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight149151.0
Non-Polymers*Number of molecules1
Total formula weight65.4
All*Total formula weight149216.4
*Water molecules are not included.

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PDB entries from 2024-07-10

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