8CQY
Crystal structure of the PTPN3 PDZ domain bound to the PBM TACE C-terminal peptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Tyrosine-protein phosphatase non-receptor type 3 | polymer | 114 | 12709.2 | 1 | UniProt (P26045) Pfam (PF00595) | Homo sapiens (human) | Protein-tyrosine phosphatase H1,PTP-H1 |
| 2 | B (B) | Disintegrin and metalloproteinase domain-containing protein 17 | polymer | 12 | 1467.6 | 1 | UniProt (P78536) | Homo sapiens | ADAM 17,Snake venom-like protease,TNF-alpha convertase,TNF-alpha-converting enzyme |
| 3 | C, D (A) | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
| 4 | E, F (A, B) | water | water | 18.0 | 22 | Chemie (HOH) |
Sequence modifications
A: -11 - 97 (UniProt: P26045)
| PDB | External Database | Details |
|---|---|---|
| Gly -16 | - | expression tag |
| Ala -15 | - | expression tag |
| Met -14 | - | expression tag |
| Gly -13 | - | expression tag |
| Ser -12 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 14176.8 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 46.0 | |
| All* | Total formula weight | 14222.8 |
