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8CQW

Crystal structure of the Candida albicans 80S ribosome in complex with Hygromycin B

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, BC
(1, AS)
25Spolymer33591085278.12Candida albicans
2B, CC
(3, AT)
5Spolymer12138943.12Candida albicans
3C, DC
(4, AU)
5.8Spolymer15850683.92Candida albicans
4D, EC
(j, AW)
60S ribosomal protein L2-Bpolymer25427366.62UniProt (A0A8H6F1X9)
Pfam (PF00181)
Pfam (PF03947)
Candida albicans
5E, FC
(k, AX)
60S ribosomal protein L3polymer38944040.82UniProt (Q59LS1)
Pfam (PF00297)
Candida albicans
6F, GC
(l, AY)
60S ribosomal protein L4-Bpolymer36339282.42UniProt (A0A8H6F4H4)
Pfam (PF00573)
Pfam (PF14374)
Candida albicans
7G, HC
(m, AZ)
Uncharacterized protein CaJ7.0206polymer29834558.02UniProt (G1UAA6)
Pfam (PF17144)
Pfam (PF14204)
Candida albicans
8H, IC
(n, BA)
60S ribosomal protein L6polymer17619798.02UniProt (Q9P834)
Pfam (PF01159)
Candida albicans
9I, JC
(o, BB)
60S ribosomal protein L7-Apolymer24127447.02UniProt (A0A8H6BVN2)
Pfam (PF08079)
Pfam (PF00327)
Candida albicans
10J, KC
(p, BC)
60S ribosomal protein L8polymer26228549.42UniProt (A0A8H6C337)
Pfam (PF01248)
Candida albicans
11K, LC
(q, BD)
60S ribosomal protein L9-Bpolymer19121755.22UniProt (A0A8H6C3N3)
Pfam (PF00347)
Candida albicans
12L, MC
(r, BE)
60S ribosomal protein L10polymer22025236.32UniProt (Q5AIB8)
Pfam (PF00252)
Candida albicans
13M, NC
(s, BF)
60S ribosomal protein L11-Bpolymer17419859.82UniProt (A0A8H6F1S5)
Pfam (PF00281)
Pfam (PF00673)
Candida albicans
14N, OC
(t, BG)
60S ribosomal protein L13polymer20223105.82UniProt (A0A8H6F5V7)
Pfam (PF01294)
Candida albicans
15O, PC
(u, BH)
60S ribosomal protein L14-Bpolymer13114748.52UniProt (A0A8H6F332)
Pfam (PF01929)
Candida albicans
16P, QC
(v, BI)
60S ribosomal protein L15-Apolymer20424389.32UniProt (Q5A6R1)
Pfam (PF00827)
Candida albicans
17Q, RC
(w, BJ)
Ribosomal protein L13polymer20022685.82UniProt (A0A8H6BZ56)
Pfam (PF00572)
Candida albicans
18R, SC
(x, BK)
Ribosomal protein L22polymer18521002.92UniProt (A0A8H6BUG0)
Pfam (PF00237)
Candida albicans
19S, TC
(y, BL)
60S ribosomal protein L18-Apolymer18620817.42UniProt (A0A8H6C4Y1)
Pfam (PF17135)
Candida albicans
20T, UC
(z, BM)
60S ribosomal protein L19-Apolymer19021942.82UniProt (A0A1D8PK40)
Pfam (PF01280)
Candida albicans
21U, VC
(0, BN)
60S ribosomal protein L20polymer17220376.92UniProt (A0A8H6BZJ3)
Pfam (PF01775)
Candida albicans
22V, WC
(2, BO)
60S ribosomal protein L21-Apolymer16018049.92UniProt (A0A8H6F1C8)
Pfam (PF01157)
Candida albicans
23W, XC
(5, BP)
60S ribosomal protein L22-Bpolymer12414107.92UniProt (A0A1D8PM41)
Pfam (PF01776)
Candida albicans
24X, YC
(6, BQ)
60S ribosomal protein L23-Apolymer13714495.02UniProt (A0A8H6C444)
Pfam (PF00238)
Candida albicans
25Y, ZC
(7, BR)
60S ribosomal protein L24-Apolymer15517430.32UniProt (A0A8H6C4U1)
Pfam (PF01246)
Candida albicans
26AD, Z
(8, BS)
60S ribosomal protein L25polymer14215873.62UniProt (A0A8H6F6A1)
Pfam (PF03939)
Pfam (PF00276)
Candida albicans
27AA, BD
(9, BT)
Ribosomal protein L24polymer12714215.52UniProt (A0A8H6F3X2)
Pfam (PF16906)
Candida albicans
28BA, CD
(AA, BU)
60S ribosomal protein L27polymer13615551.42UniProt (Q9P843)
Pfam (PF01777)
Candida albicans
29CA, DD
(AB, BV)
60S ribosomal protein L28polymer14916703.42UniProt (A0A8H6BVY8)
Pfam (PF00828)
Candida albicans
30DA, ED
(AC, BW)
60S ribosomal protein L29polymer637135.32UniProt (A0A8H6F0G8)
Pfam (PF01779)
Candida albicans
31EA, FD
(AD, BX)
60S ribosomal protein L30polymer10611520.42UniProt (A0A1D8PM75)
Pfam (PF01248)
Candida albicans
32FA, GD
(AE, BY)
60S ribosomal protein L31-Bpolymer11212993.12UniProt (A0A8H6F1M1)
Pfam (PF01198)
Candida albicans
33GA, HD
(AF, BZ)
60S ribosomal protein L32polymer13114993.72UniProt (O94008)
Pfam (PF01655)
Candida albicans
34HA, ID
(AG, CA)
60S ribosomal protein L33-Apolymer10712138.22UniProt (A0A8H6BW57)
Pfam (PF01247)
Candida albicans
35IA, JD
(AH, CB)
60S ribosomal protein L34-Bpolymer12213774.32UniProt (A0A8H6F171)
Pfam (PF01199)
Candida albicans
36JA, KD
(AI, CC)
Ribosomal protein L29polymer12014118.82UniProt (A0A8H6F6B7)
Pfam (PF00831)
Candida albicans
37KA, LD
(AJ, CD)
60S ribosomal protein L36polymer9911096.22UniProt (P47834)
Pfam (PF01158)
Candida albicansL39
38LA, MD
(AK, CE)
60S ribosomal protein L37-Bpolymer9010102.82UniProt (A0A1D8PF45)
Pfam (PF01907)
Candida albicans
39MA, ND
(AL, CF)
60S ribosomal protein L38polymer788911.52UniProt (A0A1D8PG16)
Pfam (PF01781)
Candida albicans
40NA, OD
(AM, CG)
60S ribosomal protein L39polymer516347.52UniProt (Q96W55)
Pfam (PF00832)
Candida albicansL46
41OA, PD
(AN, CH)
60S ribosomal protein L40-Bpolymer526078.42UniProt (A0A1D8PL68)
Pfam (PF01020)
Candida albicans
42PA, QD
(AO, CI)
60S ribosomal protein L41polymer253396.32UniProt (P9WER7)
Pfam (PF05162)
Candida albicans
43QA, RD
(AP, CJ)
60S ribosomal protein L42-Bpolymer10612259.62UniProt (A0A8H6BR69)
Pfam (PF00935)
Candida albicans
44RA, SD
(AQ, CK)
60S ribosomal protein L43-Apolymer9210136.82UniProt (A0A1D8PP14)
Pfam (PF01780)
Candida albicans
45SA, TD
(i, CL)
60S ribosomal protein CAALFM_C304810CApolymer26729126.12UniProt (A0A1D8PK71)
Pfam (PF09598)
Candida albicans
46TA, UD
(B, CM)
18Spolymer1787575838.62Candida albicans
47UA, VD
(C, CN)
40S ribosomal protein S0polymer26128759.32UniProt (A0A8H6C395)
Pfam (PF00318)
Candida albicans
48VA, WD
(D, CO)
40S ribosomal protein S1polymer25629041.92UniProt (A0A8H6C387)
Pfam (PF01015)
Candida albicans
49WA, XD
(E, CP)
Ribosomal protein S5polymer24926917.32UniProt (A0A8H6BZ90)
Pfam (PF00333)
Pfam (PF03719)
Candida albicans
50XA, YD
(F, CQ)
Ribosomal protein S3polymer25127313.62UniProt (A0A8H6BYS1)
Pfam (PF07650)
Pfam (PF00189)
Candida albicans
51YA, ZD
(G, CR)
40S ribosomal protein S4polymer26229435.42UniProt (A0A1D8PCI6)
Pfam (PF08071)
Pfam (PF01479)
Pfam (PF00900)
Pfam (PF00467)
Pfam (PF16121)
Candida albicans
52AE, ZA
(H, CS)
Ribosomal protein S7polymer22525319.92UniProt (A0A8H6BS29)
Pfam (PF00177)
Candida albicans
53AB, BE
(I, CT)
40S ribosomal protein S6polymer23627146.52UniProt (A0A8H6BZ37)
Pfam (PF01092)
Candida albicans
54BB, CE
(J, CU)
40S ribosomal protein S7polymer18621285.82UniProt (A0A8H6C655)
Pfam (PF01251)
Candida albicans
55CB, DE
(K, CV)
40S ribosomal protein S8polymer20622802.02UniProt (A0A8H6F0S0)
Pfam (PF01201)
Candida albicans
56DB, EE
(L, CW)
Ribosomal protein S4polymer18921765.12UniProt (A0A8H6F1X2)
Pfam (PF00163)
Pfam (PF01479)
Candida albicans
57EB, FE
(M, CX)
40S ribosomal protein S10-Apolymer11813836.82UniProt (A0A8H6BWQ8)
Pfam (PF03501)
Candida albicans
58FB, GE
(N, CY)
40S ribosomal protein S11Apolymer15517638.62UniProt (A0A1D8PN83)
Pfam (PF16205)
Pfam (PF00366)
Candida albicans
59GB, HE
(O, CZ)
40S ribosomal protein S12polymer14315715.92UniProt (A0A8H6C3A1)
Pfam (PF01248)
Candida albicans
60HB, IE
(P, DA)
40S ribosomal protein S13polymer15116976.82UniProt (A0A8H6F4G0)
Pfam (PF08069)
Pfam (PF00312)
Candida albicans
61IB, JE
(Q, DB)
40S ribosomal protein S14-Apolymer13214052.12UniProt (A0A8H6F0V4)
Pfam (PF00411)
Candida albicans
62JB, KE
(R, DC)
40S ribosomal protein S15polymer14215967.82UniProt (A0A1D8PK22)
Pfam (PF00203)
Candida albicans
63KB, LE
(S, DD)
40S ribosomal protein S16polymer14215769.52UniProt (O94017)
Pfam (PF00380)
Candida albicans
64LB, ME
(T, DE)
40S ribosomal protein S17-Bpolymer13715770.32UniProt (A0A8H6BTR7)
Pfam (PF00833)
Candida albicans
65MB, NE
(U, DF)
40S ribosomal protein S18-Bpolymer14517023.82UniProt (A0A8H6F3Y8)
Pfam (PF00416)
Candida albicans
66NB, OE
(V, DG)
40S ribosomal protein S19-Apolymer14516097.22UniProt (A0A8H6C5L4)
Pfam (PF01090)
Candida albicans
67OB, PE
(W, DH)
Ribosomal protein S10polymer11913366.52UniProt (A0A8H6BYJ9)
Pfam (PF00338)
Candida albicans
68PB, QE
(X, DI)
40S ribosomal protein S21polymer879652.82UniProt (Q9P844)
Pfam (PF01249)
Candida albicans
69QB, RE
(Y, DJ)
40S ribosomal protein S22-Apolymer13014807.22UniProt (A0A8H6F0N4)
Pfam (PF00410)
Candida albicans
70RB, SE
(Z, DK)
Ribosomal protein S23 (S12)polymer14516000.82UniProt (A0A8H6F0V0)
Pfam (PF00164)
Candida albicans
71SB, TE
(a, DL)
40S ribosomal protein S24polymer13515546.92UniProt (A0A8H6C3K1)
Pfam (PF01282)
Candida albicans
72TB, UE
(b, DM)
40S ribosomal protein S25polymer10511633.82UniProt (A0A8H6EZQ8)
Pfam (PF03297)
Candida albicans
73UB, VE
(c, DN)
40S ribosomal protein S26polymer11913606.12UniProt (A0A8H6BTS1)
Pfam (PF01283)
Candida albicans
74VB, WE
(d, DO)
40S ribosomal protein S27polymer828982.52UniProt (A0A8H6BWE6)
Pfam (PF01667)
Candida albicans
75WB, XE
(e, DP)
40S ribosomal protein S28-Bpolymer677536.82UniProt (A0A8H6C0A5)
Pfam (PF01200)
Candida albicans
76XB, YE
(f, DQ)
40S ribosomal protein S29Apolymer566615.62UniProt (A0A1D8PTR4)
Pfam (PF00253)
Candida albicans
77YB, ZE
(g, DR)
40S ribosomal protein S30polymer637127.42UniProt (A0A1D8PSK2)
Pfam (PF04758)
Candida albicans
78AF, ZB
(h, DS)
Ubiquitin-40S ribosomal protein S31 fusion proteinpolymer19322615.52UniProt (Q5A109)
Pfam (PF00240)
Pfam (PF01599)
Candida albicans
79AC, BF
(AR, DT)
Guanine nucleotide-binding protein subunit beta-like proteinpolymer31734593.92UniProt (A0A8H6C3E7)
Pfam (PF00400)
Candida albicans
80CF, GF
(P0, p0)
60S acidic ribosomal protein P0polymer31233302.62UniProt (G1UA71)
Pfam (PF00466)
Pfam (PF17777)
Pfam (PF00428)
Candida albicans
81DF
(12)
60S ribosomal protein L12-Apolymer16517791.51UniProt (A0A8H6C5X8)
Pfam (PF03946)
Pfam (PF00298)
Candida albicans
82EF, FF
(L1, l1)
Ribosomal proteinpolymer21724416.72UniProt (A0A8H6F4E7)
Pfam (PF00687)
Candida albicans
83AAA, AAB, ABA, ACA, ADA...
(3, CM, o, 6, AP...)
MAGNESIUM IONnon-polymer24.31210Chemie (MG)
84IF, WJA
(1, AS)
3-O-acetyl-2-O-(3-O-acetyl-6-deoxy-beta-D-glucopyranosyl)-6-deoxy-1-O-{[(2R,2'S,3a'R,4''S,5''R,6'S,7a'S)-5''-methyl-4''-{[(2E)-3-phenylprop-2-enoyl]oxy}decahydrodispiro[oxirane-2,3'-[1]benzofuran-2',2''-pyran]-6'-yl]carbonyl}-beta-D-glucopyranosenon-polymer804.82Chemie (3K5)
85BDA, MAB, OAB, PAB, QCA...
(AQ, DN, DQ, DS, AH...)
ZINC IONnon-polymer65.417Chemie (ZN)
86BAB, YIA
(CM, B)
HYGROMYCIN Bnon-polymer527.52Chemie (HYG)
87QAB, RAB, SAB, TAB
(1, 4, B, AS)
waterwater18.030Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains163
Total formula weight6371198.5
Non-Polymers*Number of molecules1231
Total formula weight33185.7
All*Total formula weight6404384.2
*Water molecules are not included.

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PDB entries from 2025-06-18

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