8COD

Crystal structure of S-adenosyl-L-homocysteine hydrolase from Mus musculus in complex with inosine

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Adenosylhomocysteinase	polymer	452	49917.4	2	UniProt (P50247) Pfam (PF05221) Pfam (PF00670)	Mus musculus (house mouse)	AdoHcyase,CUBP,Liver copper-binding protein,S-adenosyl-L-homocysteine hydrolase
2	C, F (A, B)	NICOTINAMIDE-ADENINE-DINUCLEOTIDE	non-polymer		663.4	2	Chemie (NAD)
3	D, G (A, B)	INOSINE	non-polymer		268.2	2	Chemie (NOS)
4	E, H (A, B)	SODIUM ION	non-polymer		23.0	2	Chemie (NA)
5	I, J (A, B)	water	water		18.0	322	Chemie (HOH)

Sequence modifications

A, B: 1 - 432 (UniProt: P50247)

PDB	External Database	Details
Met -19	-	initiating methionine
Gly -18	-	expression tag
Ser -17	-	expression tag
Ser -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
Ser -9	-	expression tag
Ser -8	-	expression tag
Gly -7	-	expression tag
Leu -6	-	expression tag
Val -5	-	expression tag
Pro -4	-	expression tag
Arg -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	99834.8
Non-Polymers*	Number of molecules	6
	Total formula weight	1909.3
All*	Total formula weight	101744.1

*Water molecules are not included.