8CLB
Colchicine bound to tubulin (T2R-TTL) complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | Tubulin alpha-1B chain | polymer | 440 | 48966.3 | 2 | UniProt (P81947) Pfam (PF00091) Pfam (PF03953) | Bos taurus (cattle) | |
| 2 | B, D (B, D) | Tubulin beta-2B chain | polymer | 431 | 48391.4 | 2 | UniProt (Q6B856) Pfam (PF00091) Pfam (PF03953) | Bos taurus (cattle) | |
| 3 | E (E) | Stathmin-4 | polymer | 121 | 14336.4 | 1 | Pfam (PF00836) UniProt (by SIFTS) (P63043) | synthetic construct | |
| 4 | F (F) | Tubulin-Tyrosine Ligase | polymer | 320 | 37184.7 | 1 | Pfam (PF03133) UniProt (by SIFTS) (A0A8V0Z8P0) | synthetic construct | |
| 5 | G, M (A, C) | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 2 | Chemie (GTP) | |||
| 6 | H, K, N, Q (A, B, C, D) | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) | |||
| 7 | I, O (A, C) | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) | |||
| 8 | J, P (B, D) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 2 | Chemie (GDP) | |||
| 9 | L, R (B, D) | N-[(7S)-1,2,3,10-tetramethoxy-9-oxo-6,7-dihydro-5H-benzo[d]heptalen-7-yl]ethanamide | non-polymer | 399.4 | 2 | Chemie (LOC) | |||
| 10 | S (F) | PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER | non-polymer | 505.2 | 1 | Chemie (ACP) | |||
| 11 | T, U, V, W, X... (A, B, C, D, E...) | water | water | 18.0 | 22 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 246236.5 | |
| Non-Polymers* | Number of molecules | 13 |
| Total formula weight | 3414.2 | |
| All* | Total formula weight | 249650.7 |
