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8CHS

Human heparan sulfate N-deacetylase-N-sulfotransferase 1 in complex with calcium, 3'-phosphoadenosine-5'-phosphosulfate and nanobody nAb13 (composite map and model).

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(D)
Nanobody nAb13 - all CA rigid fit model derived from nanobody nAb7polymer16217656.31Lama glama
2B
(A)
Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1polymer80592464.51UniProt (P52848)
Pfam (PF25119)
Pfam (PF12062)
Pfam (PF00685)
Homo sapiens (human)Glucosaminyl N-deacetylase/N-sulfotransferase 1,NDST-1,N-heparan sulfate sulfotransferase 1,N-HSST 1,[Heparan sulfate]-glucosamine N-sulfotransferase 1,HSNST 1
3C
(A)
ADENOSINE-3'-5'-DIPHOSPHATEnon-polymer427.21Chemie (A3P)
4D
(A)
CALCIUM IONnon-polymer40.11Chemie (CA)
5E
(A)
waterwater18.01Chemie (HOH)
Sequence modifications
A: 79 - 882 (UniProt: P52848)
PDBExternal DatabaseDetails
Gly 78-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight110120.8
Non-Polymers*Number of molecules2
Total formula weight467.3
All*Total formula weight110588.1
*Water molecules are not included.

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PDB entries from 2026-01-28

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