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8CEY

Structure of the mouse 8-oxoguanine DNA Glycosylase mOGG1 in complex with ligand TH11233.

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C
(A, B, C)
N-glycosylase/DNA lyasepolymer31835816.73UniProt (O08760)
Pfam (PF07934)
Pfam (PF00730)
Mus musculus (house mouse)
2D, F, G
(A, B, C)
~{N}-(3,3-dimethylcyclobutyl)imidazo[5,1-b][1,3]thiazole-3-carboxamidenon-polymer249.33Chemie (UEF)
3E
(A)
NICKEL (II) IONnon-polymer58.71Chemie (NI)
4H, I, J
(A, B, C)
waterwater18.0214Chemie (HOH)
Sequence modifications
A, B, C: 11 - 325 (UniProt: O08760)
PDBExternal DatabaseDetails
Gly 8-expression tag
Ser 9-expression tag
His 10-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight107450.0
Non-Polymers*Number of molecules4
Total formula weight806.7
All*Total formula weight108256.6
*Water molecules are not included.

248942

PDB entries from 2026-02-11

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