8CE6

Crystal structure of human Cd11b I domain in P212121 space group

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Integrin alpha-M	polymer	215	24634.9	1	UniProt (P11215) Pfam (PF00092)	Homo sapiens (human)	CD11 antigen-like family member B,CR-3 alpha chain,Cell surface glycoprotein MAC-1 subunit alpha,Leukocyte adhesion receptor MO1,Neutrophil adherence receptor
2	B, C, D, E, F... (A)	SULFATE ION	non-polymer		96.1	7	Chemie (SO4)
3	I, J, K, L, M... (A)	GLYCEROL	non-polymer		92.1	7	Chemie (GOL)
4	P (A)	CHLORIDE ION	non-polymer		35.5	1	Chemie (CL)
5	Q (A)	water	water		18.0	88	Chemie (HOH)

Sequence modifications

A: 1 - 189 (UniProt: P11215)

PDB	External Database	Details
Met -21	-	initiating methionine
His -20	-	expression tag
His -19	-	expression tag
His -18	-	expression tag
His -17	-	expression tag
His -16	-	expression tag
His -15	-	expression tag
Ser -14	-	expression tag
Ser -13	-	expression tag
Gly -12	-	expression tag
Val -11	-	expression tag
Asp -10	-	expression tag
Leu -9	-	expression tag
Gly -8	-	expression tag
Thr -7	-	expression tag
Glu -6	-	expression tag
Asn -5	-	expression tag
Leu -4	-	expression tag
Tyr -3	-	expression tag
Phe -2	-	expression tag
Gln -1	-	expression tag
Ser 0	-	expression tag
Ser 37	Thr 185	conflict
Glu 190	-	expression tag
Pro 191	-	expression tag
Glu 192	-	expression tag
Ala 193	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	24634.9
Non-Polymers*	Number of molecules	15
	Total formula weight	1352.6
All*	Total formula weight	25987.5

*Water molecules are not included.