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SummaryStructural detailsExperimental detailsFunctional detailsSequence NeighborHistoryDownloads

8CBJ

Cryo-EM structure of Otu2-bound cytoplasmic pre-40S ribosome biogenesis complex

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1b40S ribosomal protein S27-Apolymer828893.41UniProt (P35997)
Pfam (PF01667)
In PDB		Saccharomyces cerevisiae W303RP61,Small ribosomal subunit protein eS27-A,YS20
2c40S ribosomal protein S28-Apolymer677605.81UniProt (Q3E7X9)
Pfam (PF01200)
In PDB		Saccharomyces cerevisiae W303S33,Small ribosomal subunit protein eS28-A,YS27
3dRPS29A isoform 1polymer566675.71UniProt (P41057)
Pfam (PF00253)
In PDB		Saccharomyces cerevisiae W303
4e40S ribosomal protein S30-Apolymer637137.51UniProt (P0CX33)
Pfam (PF04758)
In PDB		Saccharomyces cerevisiae W303Small ribosomal subunit protein eS30-A
5gGuanine nucleotide-binding protein subunit beta-like proteinpolymer31934841.21UniProt (P38011)
Pfam (PF00400)
In PDB		Saccharomyces cerevisiae W303Receptor for activated C kinase,Receptor of activated protein kinase C 1,RACK1,Small ribosomal subunit protein RACK1
6hPre-rRNA-processing protein PNO1polymer27430380.61UniProt (A0A8H4F7A6)
Pfam (PF17903)
Pfam (PF22891)
UniProt (by SIFTS) (Q99216)
In PDB		Saccharomyces cerevisiae W303
7iENP1 isoform 1polymer48355207.41UniProt (A0A8H4BTD0)
Pfam (PF05291)
UniProt (by SIFTS) (P38333)
In PDB		Saccharomyces cerevisiae W303
8jLTV1 isoform 1polymer46353463.31UniProt (A0A8H4F8Z0)
Pfam (PF04180)
UniProt (by SIFTS) (P34078)
In PDB		Saccharomyces cerevisiae W303
9kTSR1 isoform 1polymer78890876.51UniProt (A0A8H8UMM1)
Pfam (PF22298)
Pfam (PF08142)
Pfam (PF04950)
UniProt (by SIFTS) (Q07381)
In PDB		Saccharomyces cerevisiae W303
10lnon-specific serine/threonine protein kinasepolymer42549192.91UniProt (A0A6A5Q8T7)
Pfam (PF09202)
Pfam (PF01163)
UniProt (by SIFTS) (P40160)
In PDB		Saccharomyces cerevisiae W303
11A40S ribosomal protein S0-Apolymer25228083.41UniProt (B3LI22)
Pfam (PF00318)
UniProt (by SIFTS) (P32905)
In PDB		Saccharomyces cerevisiae W303Nucleic acid-binding protein NAB1A
12B40S ribosomal protein S1-Apolymer25528798.51UniProt (P33442)
Pfam (PF01015)
In PDB		Saccharomyces cerevisiae W303RP10A,Small ribosomal subunit protein eS1-A
13C40S ribosomal protein S2polymer25427490.81UniProt (P25443)
Pfam (PF00333)
Pfam (PF03719)
In PDB		Saccharomyces cerevisiae W303Omnipotent suppressor protein SUP44,RP12,S4,Small ribosomal subunit protein uS5,YS5
14D40S ribosomal protein S3polymer24026542.81UniProt (P05750)
Pfam (PF07650)
Pfam (PF00189)
In PDB		Saccharomyces cerevisiae W303RP13,Small ribosomal subunit protein uS3,YS3
15E40S ribosomal protein S4-Bpolymer26129469.31UniProt (P0CX36)
Pfam (PF00900)
Pfam (PF00467)
Pfam (PF16121)
Pfam (PF08071)
Pfam (PF01479)
In PDB		Saccharomyces cerevisiae W303RP5,S7,Small ribosomal subunit protein eS4-B,YS6
16F40S ribosomal protein S5polymer22525072.61UniProt (P26783)
Pfam (PF00177)
In PDB		Saccharomyces cerevisiae W303RP14,S2,Small ribosomal subunit protein uS7,YS8
17G40S ribosomal protein S6-Bpolymer23627054.51UniProt (P0CX38)
Pfam (PF01092)
In PDB		Saccharomyces cerevisiae W303RP9,S10,Small ribosomal subunit protein eS6-B,YS4
18H40S ribosomal protein S7-Apolymer19021658.21UniProt (P26786)
Pfam (PF01251)
In PDB		Saccharomyces cerevisiae W303RP30,RP40,Small ribosomal subunit protein eS7-A
19I40S ribosomal protein S8-Apolymer20022537.81UniProt (P0CX39)
Pfam (PF01201)
In PDB		Saccharomyces cerevisiae W303
20J40S ribosomal protein S9-Apolymer19722487.91UniProt (O13516)
Pfam (PF00163)
Pfam (PF01479)
In PDB		Saccharomyces cerevisiae W303
21L40S ribosomal protein S11-Apolymer15617785.91UniProt (P0CX47)
Pfam (PF16205)
Pfam (PF00366)
In PDB		Saccharomyces cerevisiae W303
22M40S ribosomal protein S12polymer14315488.61UniProt (P48589)
Pfam (PF01248)
In PDB		Saccharomyces cerevisiae (baker's yeast)Small ribosomal subunit protein eS12
23N40S ribosomal protein S13polymer15117059.91UniProt (P05756)
Pfam (PF08069)
Pfam (PF00312)
In PDB		Saccharomyces cerevisiae W303S27a,Small ribosomal subunit protein uS15,YS15
24O40S ribosomal protein S14-Apolymer13714562.71UniProt (P06367)
Pfam (PF00411)
In PDB		Saccharomyces cerevisiae W303
25PRPS15 isoform 1polymer14216031.91UniProt (Q01855)
Pfam (PF00203)
In PDB		Saccharomyces cerevisiae W303
26Q40S ribosomal protein S16-Apolymer14315877.51UniProt (P0CX51)
Pfam (PF00380)
In PDB		Saccharomyces cerevisiae W303RP61R,Small ribosomal subunit protein uS9-A
27R40S ribosomal protein S17-Apolymer13615820.41UniProt (P02407)
Pfam (PF00833)
In PDB		Saccharomyces cerevisiae (baker's yeast)RP51A,Small ribosomal subunit protein eS17-A
28S40S ribosomal protein S18-Apolymer14617071.61UniProt (P0CX55)
Pfam (PF00416)
In PDB		Saccharomyces cerevisiae W303Small ribosomal subunit protein uS13-A
29T40S ribosomal protein S19-Apolymer14415942.11UniProt (P07280)
Pfam (PF01090)
In PDB		Saccharomyces cerevisiae W303RP55A,S16a,Small ribosomal subunit protein eS19-A,YP45,YS16A
30U40S ribosomal protein S20polymer12113929.01UniProt (P38701)
Pfam (PF00338)
In PDB		Saccharomyces cerevisiae W303Small ribosomal subunit protein uS10
31V40S ribosomal protein S21-Apolymer879758.81UniProt (P0C0V8)
Pfam (PF01249)
In PDB		Saccharomyces cerevisiae W303S26,Small ribosomal subunit protein eS21-A,YS25
32W40S ribosomal protein S22-Apolymer13014650.11UniProt (P0C0W1)
Pfam (PF00410)
In PDB		Saccharomyces cerevisiae W303
33X40S ribosomal protein S23-Apolymer14516073.91UniProt (P0CX29)
Pfam (PF00164)
In PDB		Saccharomyces cerevisiae W303RP37,S28,Small ribosomal subunit protein uS12-A,YS14
34Y40S ribosomal protein S24-Apolymer13515362.81UniProt (P0CX31)
Pfam (PF01282)
In PDB		Saccharomyces cerevisiae W303RP50,Small ribosomal subunit protein eS24-A
35Z40S ribosomal protein S25-Apolymer10812067.31UniProt (Q3E792)
Pfam (PF03297)
In PDB		Saccharomyces cerevisiae W303RP45,S31,Small ribosomal subunit protein eS25-A,YS23
36a20S-pre-rRNA D-site endonuclease NOB1polymer45951824.91UniProt (A0A6A5Q3F3)
Pfam (PF17146)
Pfam (PF08772)
UniProt (by SIFTS) (Q08444)
In PDB		Saccharomyces cerevisiae W303
37yrRNA adenine N(6)-methyltransferasepolymer31836003.81UniProt (A0A6A5Q6M3)
Pfam (PF00398)
UniProt (by SIFTS) (P41819)
In PDB		Saccharomyces cerevisiae W303
38220S pre-ribosomal RNApolymer2012647990.41Saccharomyces cerevisiae
39KOTU domain-containing protein 2polymer30736157.01UniProt (P38747)
Pfam (PF02338)
In PDB		Saccharomyces cerevisiae W303
40b, dZINC IONnon-polymer65.42Chemie (ZN)
412MAGNESIUM IONnon-polymer24.346Chemie (MG)
Sequence modifications
A: 1 - 252 (UniProt: B3LI22)
PDBExternal DatabaseDetails
Phe 206Asp 206conflict
K: 1 - 307 (UniProt: P38747)
PDBExternal DatabaseDetails
Ser 178Cys 178engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains39
Total formula weight1602929.1
Non-Polymers*Number of molecules48
Total formula weight1248.8
All*Total formula weight1604177.9
*Water molecules are not included.

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PDB entries from 2024-07-24

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