8CBF

SARS-CoV-2 Delta-RBD complexed with Omi-42 and Beta-49 Fabs

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (E)	Spike protein S1	polymer	202	22935.7	1	UniProt (P0DTC2) Pfam (PF09408)	Severe acute respiratory syndrome coronavirus 2
2	B (B)	Beta-49 light chain	polymer	216	23566.1	1		Homo sapiens
3	C (A)	Beta-49 heavy chain	polymer	223	23431.4	1		Homo sapiens
4	D (L)	Omi-42 light chain	polymer	215	22630.0	1		Homo sapiens
5	E (H)	Omi-42 heavy chain	polymer	230	24381.3	1		Homo sapiens
6	F (C)	alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose	branched		1219.1	1	In PDB GlyTouCan (G99801SM)
7	G, H, I (E)	GLYCEROL	non-polymer		92.1	3	Chemie (GOL)
8	J (B)	SULFATE ION	non-polymer		96.1	1	Chemie (SO4)
9	K (A)	CHLORIDE ION	non-polymer		35.5	1	Chemie (CL)
10	L, M, N, O, P (E, B, A, L, H)	water	water		18.0	236	Chemie (HOH)

Sequence modifications

E: 333 - 526 (UniProt: P0DTC2)

PDB	External Database	Details
His 327	-	expression tag
His 328	-	expression tag
His 329	-	expression tag
His 330	-	expression tag
His 331	-	expression tag
His 332	-	expression tag
Arg 452	Leu 452	variant
Lys 478	Thr 478	variant
Lys 527	-	expression tag
Lys 528	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	5
	Total formula weight	116944.5
Branched	Number of molecules	1
	Total formula weight	1219.1
Non-Polymers*	Number of molecules	5
	Total formula weight	407.8
All*	Total formula weight	118571.4

*Water molecules are not included.