8C6I
TMEM2 ectodomain
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Cell surface hyaluronidase | polymer | 1301 | 145486.5 | 1 | UniProt (Q9UHN6) Pfam (PF10162) Pfam (PF15711) Pfam (PF24606) Pfam (PF24605) | Homo sapiens (human) | Cell migration-inducing hyaluronidase 2,Transmembrane protein 2 |
| 2 | B, D (B, D) | alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 2 | In PDB GlyTouCan (G22573RC) | |||
| 3 | C, H (C, H) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 2 | In PDB GlyTouCan (G42666HT) | |||
| 4 | E (E) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 1 | In PDB GlyTouCan (G15407YE) | |||
| 5 | F (F) | alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 894.8 | 1 | In PDB GlyTouCan (G00395TQ) | |||
| 6 | G (G) | alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 1 | In PDB GlyTouCan (G81315DD) | |||
| 7 | I (A) | NICKEL (II) ION | non-polymer | 58.7 | 1 | Chemie (NI) | |||
| 8 | J (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 9 | K, L (A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) |
Sequence modifications
A: 106 - 1383 (UniProt: Q9UHN6)
| PDB | External Database | Details |
|---|---|---|
| Ala 83 | - | expression tag |
| Pro 84 | - | expression tag |
| Leu 85 | - | expression tag |
| Val 86 | - | expression tag |
| His 87 | - | expression tag |
| His 88 | - | expression tag |
| His 89 | - | expression tag |
| His 90 | - | expression tag |
| His 91 | - | expression tag |
| His 92 | - | expression tag |
| Ala 93 | - | expression tag |
| Leu 94 | - | expression tag |
| Asp 95 | - | expression tag |
| Glu 96 | - | expression tag |
| Asn 97 | - | expression tag |
| Leu 98 | - | expression tag |
| Tyr 99 | - | expression tag |
| Phe 100 | - | expression tag |
| Gln 101 | - | expression tag |
| Gly 102 | - | expression tag |
| Ala 103 | - | expression tag |
| Leu 104 | - | expression tag |
| Ala 105 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 145486.5 | |
| Branched | Number of molecules | 7 |
| Total formula weight | 4576.2 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 536.6 | |
| All* | Total formula weight | 150599.3 |
