8C1P
Active state homomeric GluA1 AMPA receptor in complex with TARP gamma 3
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Glutamate receptor 1 flip isoform | polymer | 915 | 102661.9 | 4 | UniProt (P19490) Pfam (PF01094) Pfam (PF10613) Pfam (PF00060) | Rattus norvegicus (Norway rat) | GluR-1,AMPA-selective glutamate receptor 1,GluR-A,GluR-K1,Glutamate receptor ionotropic,AMPA 1,GluA1 |
| 2 | E, F, G, H (E, F, G, H) | Voltage-dependent calcium channel gamma-3 subunit | polymer | 314 | 35435.3 | 4 | UniProt (Q8VHX0) Pfam (PF00822) | Rattus norvegicus (Norway rat) | Neuronal voltage-gated calcium channel gamma-3 subunit,Transmembrane AMPAR regulatory protein gamma-3,TARP gamma-3 |
| 3 | I, M, R, V (A, B, C, D) | CYCLOTHIAZIDE | non-polymer | 389.9 | 4 | Chemie (CYZ) PubChem (2910) PubChem (21550932) PubChem (177678892) PubChem (44582559) PubChem (52949708) PubChem (657321) PubChem (5288009) PubChem (92142359) PubChem (98047041) PubChem (101691639) PubChem (5388988) PubChem (92143401) PubChem (92215537) PubChem (6603794) PubChem (98047042) PubChem (101691640) PubChem (11972587) PubChem (131842006) | |||
| 4 | J, N, P, S, W... (A, B, C, D) | PALMITIC ACID | non-polymer | 256.4 | 6 | Chemie (PLM) | |||
| 5 | K, O, T, X (A, B, C, D) | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate | non-polymer | 356.5 | 4 | Chemie (OLC) PubChem (25021708) PubChem (46840179) PubChem (54294271) PubChem (54294270) PubChem (33022) PubChem (5283468) PubChem (5364833) PubChem (11451146) PubChem (12178130) | |||
| 6 | L, Q, U, Z (A, B, C, D) | GLUTAMIC ACID | non-polymer | 147.1 | 4 | Chemie (GLU) PubChem (611) PubChem (23327) PubChem (33032) | |||
| 7 | AA, BA (E, G) | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate | non-polymer | 760.1 | 2 | Chemie (POV) PubChem (65167) PubChem (168614) PubChem (6070971) PubChem (5497103) PubChem (6436017) PubChem (6506401) PubChem (10908846) | |||
| 8 | CA, DA, EA, FA, GA... (A, B, C, D, E...) | water | water | 18.0 | 64 | Chemie (HOH) |
Sequence modifications
A, B, C, D: -25 - 889 (UniProt: P19490)
| PDB | External Database | Details |
|---|---|---|
| Asp -6 | - | insertion |
| Tyr -5 | - | insertion |
| Lys -4 | - | insertion |
| Asp -3 | - | insertion |
| Asp -2 | - | insertion |
| Asp -1 | - | insertion |
| Asp 0 | - | insertion |
| Lys 1 | - | insertion |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 552389.0 | |
| Non-Polymers* | Number of molecules | 20 |
| Total formula weight | 6632.9 | |
| All* | Total formula weight | 559021.9 |
