8C1L
Crystal structure of HNF4 alpha LBD in complexes with palmitic acid and GRIP-1 peptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Hepatocyte nuclear factor 4-alpha | polymer | 232 | 26211.5 | 2 | UniProt (P41235) Pfam (PF00104) | Homo sapiens (human) | HNF-4-alpha,Nuclear receptor subfamily 2 group A member 1,Transcription factor 14,TCF-14,Transcription factor HNF-4 |
| 2 | C, D (D, E) | Nuclear receptor coactivator 2 | polymer | 9 | 1161.4 | 2 | UniProt (Q15596) | Homo sapiens | NCoA-2,Class E basic helix-loop-helix protein 75,bHLHe75,Transcriptional intermediary factor 2,hTIF2 |
| 3 | E, H (A, B) | PALMITIC ACID | non-polymer | 256.4 | 2 | Chemie (PLM) | |||
| 4 | F, G, I (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 3 | Chemie (EDO) | |||
| 5 | J, K (A, B) | water | water | 18.0 | 90 | Chemie (HOH) |
Sequence modifications
A, B: 139 - 368 (UniProt: P41235)
| PDB | External Database | Details |
|---|---|---|
| Ser 137 | - | expression tag |
| Met 138 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 54745.9 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 699.1 | |
| All* | Total formula weight | 55445.0 |
