8C12
Identification of an intermediate activation state of PAK5 reveals a novel mechanism of kinase inhibition.
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (AAA) | Serine/threonine-protein kinase PAK 5 | polymer | 295 | 33700.1 | 1 | UniProt (Q9P286) Pfam (PF00069) | Homo sapiens (human) | p21-activated kinase 5,PAK-5,p21-activated kinase 7,PAK-7 |
| 2 | B (BBB) | PAK5-Af17 | polymer | 106 | 12355.1 | 1 | synthetic construct | ||
| 3 | C, D (AAA, BBB) | water | water | 18.0 | 195 | Chemie (HOH) |
Sequence modifications
AAA: 426 - 719 (UniProt: Q9P286)
| PDB | External Database | Details |
|---|---|---|
| Met 425 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 46055.1 | |
| All* | Total formula weight | 46055.1 |
