8BYU
Crystal Structure of HexaBody-CD38 Fab in complex with CD38
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | H | Fab Heavy Chain | polymer | 235 | 25112.2 | 1 | Homo sapiens | ||
2 | L | Fab Light Chain | polymer | 214 | 23383.9 | 1 | Homo sapiens | ||
3 | A | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | polymer | 262 | 30478.5 | 1 | UniProt (P28907) Pfam (PF02267) In PDB | Homo sapiens (human) | 2'-phospho-ADP-ribosyl cyclase,2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase,2'-phospho-cyclic-ADP-ribose transferase,ADP-ribosyl cyclase 1,ADPRC 1,Cyclic ADP-ribose hydrolase 1,cADPr hydrolase 1,T10 |
4 | H, A | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
5 | H, L | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
6 | A | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
7 | water | water | 18.0 | 619 | Chemie (HOH) |
Sequence modifications
A: 45 - 300 (UniProt: P28907)
PDB | External Database | Details |
---|---|---|
His 39 | - | expression tag |
His 40 | - | expression tag |
His 41 | - | expression tag |
His 42 | - | expression tag |
His 43 | - | expression tag |
His 44 | - | expression tag |
Thr 49 | Gln 49 | conflict |
Asp 100 | Asn 100 | conflict |
Ala 164 | Asn 164 | conflict |
Asp 209 | Asn 209 | conflict |
Asp 219 | Asn 219 | conflict |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 78974.6 | |
Non-Polymers* | Number of molecules | 7 |
Total formula weight | 596.5 | |
All* | Total formula weight | 79571.1 |