8BWX
Fragment-linked stabilizer for 14-3-3 and ERa (1075298)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | 14-3-3 protein sigma | polymer | 236 | 26558.9 | 1 | UniProt (P31947) Pfam (PF00244) | Homo sapiens (human) | Epithelial cell marker protein 1,Stratifin |
| 2 | B (B) | ERalpha peptide | polymer | 5 | 613.6 | 1 | UniProt (by SIFTS) (P03372) | Homo sapiens | |
| 3 | C (A) | 4-azanyl-~{N}-[3-(5-carbamimidoylthiophen-3-yl)phenyl]-1-(4-chloranylphenoxy)cyclohexane-1-carboxamide | non-polymer | 469.0 | 1 | Chemie (RZT) | |||
| 4 | D, E (A, B) | water | water | 18.0 | 326 | Chemie (HOH) |
Sequence modifications
A: 1 - 231 (UniProt: P31947)
| PDB | External Database | Details |
|---|---|---|
| Gly -4 | - | expression tag |
| Ala -3 | - | expression tag |
| Met -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 27172.5 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 469.0 | |
| All* | Total formula weight | 27641.5 |
