8BWO
Cryo-EM structure of nanodisc-reconstituted human MRP4 with E1202Q mutation (outward-facing occluded conformation)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | ATP-binding cassette sub-family C member 4 | polymer | 1325 | 149692.9 | 1 | UniProt (O15439) Pfam (PF00664) Pfam (PF00005) In PDB | Homo sapiens (human) | MRP/cMOAT-related ABC transporter,Multi-specific organic anion transporter B,MOAT-B,Multidrug resistance-associated protein 4 |
| 2 | A | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 2 | Chemie (ATP) | |||
| 3 | A | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) |
Sequence modifications
A: 1 - 1325 (UniProt: O15439)
| PDB | External Database | Details |
|---|---|---|
| Gln 1202 | Glu 1202 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 149692.9 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1063.0 | |
| All* | Total formula weight | 150755.9 |
