8BVS
Cryo-EM structure of rat SLC22A6 bound to tenofovir
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Solute carrier family 22 member 6 | polymer | 547 | 60553.6 | 1 | UniProt (O35956) Pfam (PF00083) In PDB | Rattus norvegicus (Norway rat) | Organic anion transporter 1,rOAT1,renal organic anion transporter 1,rROAT1 |
| 2 | B | Synthetic nanobody (Sybody) | polymer | 146 | 16079.8 | 1 | synthetic construct | ||
| 3 | A | [2-(6-AMINO-9H-PURIN-9-YL)-1-METHYLETHOXY]METHYLPHOSPHONIC ACID | non-polymer | 287.2 | 1 | Chemie (TFO) | |||
| 4 | A | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) |
Sequence modifications
A: 1 - 542 (UniProt: O35956)
| PDB | External Database | Details |
|---|---|---|
| Glu 542 | Gln 542 | conflict |
| Asn 543 | - | expression tag |
| Leu 544 | - | expression tag |
| Tyr 545 | - | expression tag |
| Phe 546 | - | expression tag |
| Gln 547 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 76633.4 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 322.7 | |
| All* | Total formula weight | 76956.0 |
