8BSF
CRYSTAL STRUCTURE OF SARS-COV-2 RECEPTOR BINDING DOMAIN (RBD-beta variant) in complex with 3D2 Fab
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Spike protein S1 | polymer | 231 | 26129.4 | 1 | UniProt (P0DTC2) Pfam (PF09408) | Severe acute respiratory syndrome coronavirus 2 | |
| 2 | B (H) | 3D2 FAB HEAVY CHAIN | polymer | 231 | 24568.5 | 1 | Homo sapiens (Human) | ||
| 3 | C (L) | 3D2 FAB LIGHT CHAIN | polymer | 216 | 22861.3 | 1 | Homo sapiens (Human) | ||
| 4 | D (A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
| 5 | E, F, G, H (H, L) | GLYCEROL | non-polymer | 92.1 | 4 | Chemie (GOL) | |||
| 6 | I, J, K (A, H, L) | water | water | 18.0 | 123 | Chemie (HOH) |
Sequence modifications
A: 319 - 541 (UniProt: P0DTC2)
| PDB | External Database | Details |
|---|---|---|
| Asn 417 | Lys 417 | engineered mutation |
| Lys 484 | Glu 484 | engineered mutation |
| Tyr 501 | Asn 501 | engineered mutation |
| Ser 542 | - | expression tag |
| Gly 543 | - | expression tag |
| His 544 | - | expression tag |
| His 545 | - | expression tag |
| His 546 | - | expression tag |
| His 547 | - | expression tag |
| His 548 | - | expression tag |
| His 549 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 73559.2 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 589.6 | |
| All* | Total formula weight | 74148.8 |
