8BSF

CRYSTAL STRUCTURE OF SARS-COV-2 RECEPTOR BINDING DOMAIN (RBD-beta variant) in complex with 3D2 Fab

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Spike protein S1	polymer	231	26129.4	1	UniProt (P0DTC2) Pfam (PF09408) In PDB	Severe acute respiratory syndrome coronavirus 2
2	H	3D2 FAB HEAVY CHAIN	polymer	231	24568.5	1		Homo sapiens (Human)
3	L	3D2 FAB LIGHT CHAIN	polymer	216	22861.3	1		Homo sapiens (Human)
4	A	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	1	Chemie (NAG)
5	H, L	GLYCEROL	non-polymer		92.1	4	Chemie (GOL)
6		water	water		18.0	123	Chemie (HOH)

Sequence modifications

A: 319 - 541 (UniProt: P0DTC2)

PDB	External Database	Details
Asn 417	Lys 417	engineered mutation
Lys 484	Glu 484	engineered mutation
Tyr 501	Asn 501	engineered mutation
Ser 542	-	expression tag
Gly 543	-	expression tag
His 544	-	expression tag
His 545	-	expression tag
His 546	-	expression tag
His 547	-	expression tag
His 548	-	expression tag
His 549	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	73559.2
Non-Polymers*	Number of molecules	5
	Total formula weight	589.6
All*	Total formula weight	74148.8

*Water molecules are not included.