8BR0
ExoY Nucleotidyl Cyclase domain from Vibrio nigripulchritudo MARTX toxin (residue Q3455 to L3863) in complex with 3'deoxyCTP and two manganese cations bound to Latrunculin-B-ADP-Mn-actin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | Actin, alpha skeletal muscle, intermediate form | polymer | 375 | 41862.6 | 2 | UniProt (P68135) Pfam (PF00022) | Oryctolagus cuniculus (rabbit) | |
| 2 | B, D (B, D) | Putative Adenylate cyclase,Profilin-1 | polymer | 591 | 65232.9 | 2 | UniProt (A0A6N3LUE9) UniProt (P07737) Pfam (PF00235) UniProt (by SIFTS) (A0A9P1NJI6) | Vibrio nigripulchritudo SFn135 | Epididymis tissue protein Li 184a,Profilin I |
| 3 | E, K (A, C) | LATRUNCULIN B | non-polymer | 395.5 | 2 | Chemie (LAB) PubChem (3892) PubChem (72940) PubChem (5352046) PubChem (5353712) PubChem (6436219) PubChem (10000783) PubChem (14504487) PubChem (16760044) PubChem (20054954) PubChem (22832299) PubChem (23424960) PubChem (23863831) PubChem (25215545) PubChem (56928133) PubChem (98044135) PubChem (57370013) PubChem (162928966) PubChem (59169653) PubChem (59431496) PubChem (67441199) PubChem (67441200) PubChem (88895461) PubChem (90912141) PubChem (92209860) PubChem (98044136) PubChem (98044137) PubChem (129388766) PubChem (129388767) PubChem (146159701) PubChem (154825202) PubChem (162928961) PubChem (162928962) PubChem (162928963) PubChem (162928964) PubChem (162928965) PubChem (162928967) PubChem (163195209) PubChem (168317464) PubChem (171039486) | |||
| 4 | F, L (A, C) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 2 | Chemie (ADP) | |||
| 5 | G, H, I, M, N... (A, B, C, D) | MANGANESE (II) ION | non-polymer | 54.9 | 6 | Chemie (MN) PubChem (27854) | |||
| 6 | J, P (B, D) | 3'-DEOXY-CYTIDINE-5'-TRIPHOSPHATE | non-polymer | 467.2 | 2 | Chemie (CH1) PubChem (153054) PubChem (22677567) PubChem (173899006) PubChem (88032986) PubChem (102601463) PubChem (118151180) | |||
| 7 | Q, R, S, T (A, B, C, D) | water | water | 18.0 | 541 | Chemie (HOH) |
Sequence modifications
B, D: 455 - 896 (UniProt: A0A6N3LUE9)
B, D: 903 - 1041 (UniProt: P07737)
| PDB | External Database | Details |
|---|---|---|
| Gly 451 | - | expression tag |
| Pro 452 | - | expression tag |
| Gly 453 | - | expression tag |
| Ser 454 | - | expression tag |
| Pro 897 | - | linker |
| Pro 898 | - | linker |
| Pro 899 | - | linker |
| Pro 900 | - | linker |
| Gly 901 | - | linker |
| Gly 902 | - | linker |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 214190.9 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 2909.4 | |
| All* | Total formula weight | 217100.3 |
