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8BOS

Transition state analogue complex of small G protein and its GAP effector

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(R)
GTPase HRaspolymer16618875.21UniProt (P01112)
Pfam (PF00071)
Homo sapiens (human)H-Ras-1,Ha-Ras,Transforming protein p21,c-H-ras,p21ras
2B
(G)
Ras GTPase-activating protein 1polymer33137780.81UniProt (P20936)
Pfam (PF00616)
Homo sapiens (human)GAP,GTPase-activating protein,RasGAP,Ras p21 protein activator,p120GAP
3C
(R)
GUANOSINE-5'-DIPHOSPHATEnon-polymer443.21Chemie (GDP)
4D
(R)
TRIFLUOROMAGNESATEnon-polymer81.31Chemie (MGF)
5E
(R)
MAGNESIUM IONnon-polymer24.31Chemie (MG)
6F
(G)
GUANIDINEnon-polymer59.11Chemie (GAI)
7G, H
(R, G)
waterwater18.058Chemie (HOH)
Sequence modifications
G: 713 - 1042 (UniProt: P20936)
PDBExternal DatabaseDetails
Gly 712-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight56656.0
Non-Polymers*Number of molecules4
Total formula weight607.9
All*Total formula weight57263.9
*Water molecules are not included.

246031

PDB entries from 2025-12-10

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