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8BOS

Transition state analogue complex of small G protein and its GAP effector

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(R)
GTPase HRaspolymer16618875.21UniProt (P01112)
Pfam (PF00071)
Homo sapiens (human)H-Ras-1,Ha-Ras,Transforming protein p21,c-H-ras,p21ras
2B
(G)
Ras GTPase-activating protein 1polymer33137780.81UniProt (P20936)
Pfam (PF00616)
Homo sapiens (human)GAP,GTPase-activating protein,RasGAP,Ras p21 protein activator,p120GAP
3C
(R)
GUANOSINE-5'-DIPHOSPHATEnon-polymer443.21Chemie (GDP)
PubChem (136073927)
PubChem (135398619)
PubChem (135402030)
PubChem (135431654)
PubChem (135566337)
PubChem (135760556)
PubChem (136026707)
PubChem (136053418)
PubChem (136663964)
PubChem (136664748)
PubChem (136759848)
PubChem (136759849)
PubChem (136759850)
PubChem (136836636)
PubChem (136847074)
PubChem (172898537)
4D
(R)
TRIFLUOROMAGNESATEnon-polymer81.31Chemie (MGF)
5E
(R)
MAGNESIUM IONnon-polymer24.31Chemie (MG)
PubChem (888)
6F
(G)
GUANIDINEnon-polymer59.11Chemie (GAI)
PubChem (3520)
7G, H
(R, G)
waterwater18.058Chemie (HOH)
Sequence modifications
G: 713 - 1042 (UniProt: P20936)
PDBExternal DatabaseDetails
Gly 712-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight56656.0
Non-Polymers*Number of molecules4
Total formula weight607.9
All*Total formula weight57263.9
*Water molecules are not included.

251422

PDB entries from 2026-04-01

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