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8BLR

G13D mutant of KRAS4b (2-169) bound to GDP with the switch-I in fully open conformation

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
GTPase KRas, N-terminally processedpolymer17019462.91UniProt (P01116)
Pfam (PF00071)
Homo sapiens (human)
2B
(A)
GUANOSINE-5'-DIPHOSPHATEnon-polymer443.21Chemie (GDP)
3C
(A)
waterwater18.0173Chemie (HOH)
Sequence modifications
A: 2 - 169 (UniProt: P01116)
PDBExternal DatabaseDetails
Gly 0-expression tag
Gly 1-expression tag
Asp 13Gly 13variant
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight19462.9
Non-Polymers*Number of molecules1
Total formula weight443.2
All*Total formula weight19906.1
*Water molecules are not included.

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PDB entries from 2024-11-13

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