8BK3
Crystal structure of the transpeptidase LdtMt2 from Mycobacterium tuberculosis in complex with diepoxide ketone 1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | L,D-transpeptidase 2 | polymer | 355 | 38009.1 | 2 | UniProt (O53223) Pfam (PF17964) Pfam (PF03734) UniProt (by SIFTS) (I6Y9J2) | Mycobacterium tuberculosis | LDT 2,Ldt(Mt2) |
| 2 | C (A) | 1-[(2~{S},3~{R})-3-phenyloxiran-2-yl]ethanone | non-polymer | 162.2 | 1 | Chemie (QXU) | |||
| 3 | D, E, F, I (A, B) | NITRATE ION | non-polymer | 62.0 | 4 | Chemie (NO3) | |||
| 4 | G (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 5 | H (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 6 | J, K (B) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 2 | Chemie (DMS) | |||
| 7 | L, M (A, B) | water | water | 18.0 | 743 | Chemie (HOH) |
Sequence modifications
A, B: 56 - 408 (UniProt: O53223)
| PDB | External Database | Details |
|---|---|---|
| Gln 54 | - | expression tag |
| Ser 55 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 76018.3 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 720.6 | |
| All* | Total formula weight | 76738.9 |
